QUANTITATIVE EEG IN LOW LEVEL INFORMATION PROCESSING IN LEARNING DISABILITIES

LDRC的基本假设是，神经发育 支持低级信息处理(LLIP)的构建块包括 尤其是学习障碍(LD)儿童。这种情况 导致在正常情况下快速处理时间的缺陷 信息。项目IV的主要目标是使用工具提供 是神经生理学所独有的，这是对 学习障碍儿童LLIP的假设差异 残疾儿童和没有残疾的儿童。 作为与发改委其他项目协调努力的一部分， 项目四将评估200名学习困难儿童和200名儿童。 标准化样本，作为项目I的一部分，将被定义并分成 根据“生理学--”的长处和短处进行分组 听觉中时间信息处理的合理变量， 视觉和运动测序领域。项目IV支持基本的 概述中所述的最不发达国家研究中心的前提，即学习 残疾是一种功能缺陷。项目IV将依赖于 对时间方面敏感的脑电数据的量化 神经功能： 1)推导出对LLIP敏感的神经生理指标 视觉、听觉和运动系统中的时间信息处理 这些领域是学习障碍的特征。 2)应用标准的神经生理测试电池，该电池已用于 学习障碍儿童与正常儿童的区别及其发展 基于电池的神经生理处理措施，包括皮质- 皮质连通性、光谱相干性；处理速度和 效率、诱发电位潜伏期、诱发电位来源和数目 发电机，脑电源定位(BESA)。

The underlying hypothesis of the LDRC is that the neurodevelopmental building blocks that support low level information processing (LLIP) are specifically disordered in learning disabled (LD) children. This condition results in a deficit in the normally rapid processing of temporal information. The primary goal of Project IV is to provide, using the tools that are unique to neurophysiology, an independent validation of the hypothesized differences in LLIP between children with learning disabilities and children without such disabilities. As part of a coordinated effort with the other projects in the LDRC, Project IV will evaluate 200 LD children and 200 children in the standardization sample who, as part of Project I, will be defined and sub- grouped based on profiles of strengths and deficits on "physiological- plausible" variables of temporal information processing in the auditory, visual, and motor sequencing domains. Project IV supports the basic premise of the LDRC as stated in the Overview, namely that learning disabilities represent a functional deficit. Project IV will rely on the quantification of EEG data which is sensitive to the temporal aspects of neural function to: 1) Derive neurophysiological measures of LLIP which are sensitive to temporal information processing in visual, auditory, and motor systems domains and which characterize learning disabilities. 2) Apply a standard neurophysiological test battery which has been used to differentiate LD from normal children and to develop based upon this battery basis neurophysiologic measures of processing including cortical- cortical connectivity, spectral coherence; processing speed and efficiency, evoked potential latency; and source and number of EP generators, Brain Electrical Source Localization (BESA).