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Ethnicity and COVID-19: investigating the determinants of excess risk in UK Biobank

Ethnicity and COVID-19: investigating the determinants of excess risk in UK Biobank
种族和 COVID-19:调查英国生物银行过度风险的决定因素
批准号:
MR/V020536/1
负责人:
Thomas Yates
金额:
$16.19万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2020
资助国家:
英国
项目状态:
已结题
起止时间:
2020 至 --

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中文摘要
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英文摘要
What is the problem? People from minority ethnic groups seem to be disproportionally affected by COVID-19, particularly South Asian and Black and African Caribbean communities.What has been done so far? National datasets have shown that minority ethnic groups are up to 4 times more likely to die from COVID-19. However, the reason for this increased risk is not known. What are we going to do?We will use a large dataset, called UK Biobank, which has been linked to national COVID-19 data. Within this dataset, we will use statistical modelling to examine whether the increased risk in minority ethnic groups is explained by differences in underlying health status, lifestyle behaviours such as physical activity, and environmental factors such as air pollution or measures of social inequality.Why is this important?This work will start to unpick why minority ethnic groups may be at increased risk and whether this increased risk is spread equality across the population. For example, is the increased risk explained by a higher burden of other diseases such as heart disease or diabetes or by living in more polluted areas? Do otherwise healthy individuals from minority ethnic groups still have an increased risk? Addressing these question will help inform public health priorities and actions.
期刊论文(10)
专著(0)
科研奖励(0)
会议论文
Association between household size and COVID-19: A UK Biobank observational study.
家庭规模与Covid-19之间的关联:英国生物库观察研究。
DOI: 10.1177/01410768211073923
发表时间: 2022-04
期刊: Journal of the Royal Society of Medicine
影响因子: 17.3
作者: [Gillies CL, Rowlands AV, Razieh C, Nafilyan V, Chudasama Y, Islam N, Zaccardi F, Ayoubkhani D, Lawson C, Davies MJ, Yates T, Khunti K]
通讯作者: Khunti K
DOI: 10.1186/s12879-021-06600-y
发表时间: 2021-09-04
期刊: BMC infectious diseases
影响因子: 3.7
作者: [Chudasama YV, Zaccardi F, Gillies CL, Razieh C, Yates T, Kloecker DE, Rowlands AV, Davies MJ, Islam N, Seidu S, Forouhi NG, Khunti K]
通讯作者: Khunti K
DOI: 10.1093/pubmed/fdab400
发表时间: 2023-03-14
期刊: Journal of public health (Oxford, England)
影响因子: --
作者: [Gaughan CH, Razieh C, Khunti K, Banerjee A, Chudasama YV, Davies MJ, Dolby T, Gillies CL, Lawson C, Mirkes EM, Morgan J, Tingay K, Zaccardi F, Yates T, Nafilyan V]
通讯作者: Nafilyan V
RESET: REmission of diabetes and improved diastolic function by combining Structured Exercise with meal replacemenT and food reintroduction.
  • 批准号:
    MR/T031816/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $43.16万
  • 财政年份:
    2020
  • 负责人:
    Thomas Yates
  • 依托单位:
Sedentary behaviour in older adults: investigating a new therapeutic paradigm
  • 批准号:
    MR/K025090/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $108.7万
  • 财政年份:
    2013
  • 负责人:
    Thomas Yates
  • 依托单位:
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  • 批准号:
    82370569
  • 项目类别:
    面上项目
  • 资助金额:
    49万元
  • 批准年份:
    2023
  • 负责人:
    李啸峰
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COVID-19疫情对我国儿童生长发育影响的异质性研究
  • 批准号:
    42371429
  • 项目类别:
    面上项目
  • 资助金额:
    52.00万元
  • 批准年份:
    2023
  • 负责人:
    张知新
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传染病模型的稳态切换过程研究及其在治疗COVID-19中的应用
  • 批准号:
    LQ23A010016
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2023
  • 负责人:
    罗敏
  • 依托单位:
“湿漫膜原”视角下研究加味达原饮重塑COVID-19“免疫炎症稳态”的分子机制:TLR4介导IRF3/NF-κB通路串扰
  • 批准号:
    82374291
  • 项目类别:
    面上项目
  • 资助金额:
    48万元
  • 批准年份:
    2023
  • 负责人:
    张传涛
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