课题基金 / 基金详情

EFFECT OF CYSTEINE ON AUTOXIDATION OF HOMOCYSTEINE & VASCULAR DISEASE

EFFECT OF CYSTEINE ON AUTOXIDATION OF HOMOCYSTEINE & VASCULAR DISEASE
半胱氨酸对同型半胱氨酸自氧化的影响
批准号:
6118836
负责人:
NEIL HOGG
金额:
$0.1万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-03-01 至 2000-02-29

项目摘要

项目成果

NEIL HOGG的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
This study examines the effect of cysteine on the autoxidation of homocysteine, a process that has been implicated in the pathological mechanism of hyperhomocysteinemia with respect to arteriosclerosis and vascular disease. It is shown that homocysteine autoxidizes at a much slower rate that cysteine, but that low concentrations of cysteine dramatically accelerate homocysteine oxidation and increase the rate of homocysteine-dependent oxygen consumption. It is proposed that the major role of homocysteine is to reduce cystine to cysteine, and that cysteine autoxidation is the mechanism by which thiol-dependent oxidative stress occurs.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
2012 Oxygen Radicals Gordon Research Conference
  • 批准号:
    8255109
  • 项目类别:
  • 资助金额:
    $2.25万
  • 财政年份:
    2012
  • 负责人:
    NEIL HOGG
  • 依托单位:
Summer Research Experiences for Undergraduates
  • 批准号:
    6561443
  • 项目类别:
  • 资助金额:
    $5.95万
  • 财政年份:
    2003
  • 负责人:
    NEIL HOGG
  • 依托单位:
Summer Research Experiences for Undergraduates
  • 批准号:
    6737558
  • 项目类别:
  • 资助金额:
    $6.11万
  • 财政年份:
    2003
  • 负责人:
    NEIL HOGG
  • 依托单位:
Summer Research Experiences for Undergraduates
  • 批准号:
    7057787
  • 项目类别:
  • 资助金额:
    $6.45万
  • 财政年份:
    2003
  • 负责人:
    NEIL HOGG
  • 依托单位:
海外基金