CO-CONNECT: COVID - Curated and Open aNalysis aNd rEsearCh plaTform

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CO-CONNECT is a collaborative project and it has four CO-PIs: Jefferson (Dundee), Sheikh (Edinburgh), Hopkins (PHE) and Quinlan (Nottingham).The current COVID-19 pandemic has caused hundreds of thousands of deaths, severely strained health systems and damaged economies across the world. At this time there is limited evidence that people who have recovered from COVID-19 and have antibodies are protected from a second infection and if so, how long that lasts. Understanding who is immune is vital to protect vulnerable individuals, to safely scale back population-based interventions and for managing disease transmission. The data which can help us to answer these key questions have been collected across the UK by a range of research groups and within clinical primary and secondary care settings. As this is a new disease, the standards for antibody data capture are in their infancy so some of the details need to answer the key questions are not being captured systematically. The fragmented landscape of data means that it can be challenging for public health groups and researchers to find and access the high-quality data they need at pace. We will: - Standardise antibody data collection across the UK - Configure an infrastructure which enables trustworthy, fast, de-identified, secure analysis of data sets from across multiple sources - Answer key questions about immunity to COVID-19 and the implications for patient outcomes.