Development of a novel bioengineered tissue construct for repairing the eye.

开发一种用于修复眼睛的新型生物工程组织结构。

• 批准号: nhmrc : 553038
• 负责人: Prof Damien Harkin
• 金额: $ 22.39万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-novel-bioengineered-repairing-eye/81568
• 关键词: Development; novel; bioengineered; tissue; construct

Corneal diseases are often treated using donor tissue transplants. Nevertheless, donor tissue is unsuitable for treating the peripheral or limbal margin of the cornea. We have therefore developed a way to transplant sheets of limbal tissue (epithelium) grown in the laboratory from a patient's own cells, but this tissue lacks a foundation of connective tissue that we believe is essential for sustained healing. Thus, our aim is to develop a novel limbal transplant which contains both layers.

角膜疾病通常使用供体组织移植来治疗。然而，供体组织不适合用于治疗角膜的周边或角膜缘。因此，我们已经开发出一种方法来移植在实验室中从患者自身细胞中生长的角膜缘组织（上皮），但这种组织缺乏结缔组织的基础，我们认为这是持续愈合所必需的。因此，我们的目标是开发一种新的角膜缘移植，其中包含两个层。