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PELLET GASTRIC EMPTYING TEST (PGET)

PELLET GASTRIC EMPTYING TEST (PGET)
颗粒胃排空试验 (PGET)
批准号：
6297024
负责人：
GORDON L AMIDON
金额：
$0.02万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6297024
关键词：
clearance rate clinical trials dosage forms gastrointestinal absorption /transport human subject noninvasive diagnosis particle stomach emptying

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中文摘要
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英文摘要
In order to evaluate the influence of particle size on gastric emptying this randomized four-way crossover trial will be conducted in 12 healthy volunteers. This study is designed to validate that marker drugs of different particle sizes can be used as to assess gastric emptying. This study utilizes a novel methodology which has potential for future application as a non-invasive method for measuring gastric emptying.
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Novel Transport and Activation Strategy to Improve the Bioavailability of Targeted Prodrugs
Novel Transport and Activation Strategy to Improve the Bioavailability of Targeted Prodrugs
INTESTINAL PERMEABILITY OF CYCLOSPORIN A
INTESTINAL PERMEABILITY OF CYCLOSPORIN A
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