SABRIL (VIGABATRIM) VS CARBAMAZEPINE IN PTS W/NON-REFRACTORY COMPLEX SEIZURES

SABRIL (VIGABATRIM) 对比卡马西平治疗非难治性复杂性癫痫发作的 PTS

• 批准号: 6113596
• 负责人: GREGORY Y CHANG
• 金额: $ 3.97万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6113596
• 关键词: anticonvulsants; brain disorder chemotherapy; carbamazepine; clinical research; clinical trials; combination chemotherapy; drug screening /evaluation; human subject; human therapy evaluation; partial seizure; phenytoin

The primary objective of this study is to determine the efficacy of Sabril as add-on therapy in non-refractory patients who experience occasional complex partial seizure while on carbarmazepine monotherapy. Specifically, the efficacy, safety and impact on quality of life of rational polytherapy with Sabril and carbamazepine, in comparison to monotherapy with carbamazepine, will be assessed.

本研究的主要目的是确定 Sabril 的功效 作为偶尔经历过的非难治性患者的附加治疗 卡马西平单药治疗时出现复杂的部分性癫痫发作。 具体而言，其有效性、安全性以及对生活质量的影响 与 Sabril 和卡马西平的合理综合治疗相比 将评估卡马西平单一疗法。