SABRIL (VIGABATRIM) VS CARBAMAZEPINE IN PTS W/NON-REFRACTORY COMPLEX SEIZURES

SABRIL (VIGABATRIM) 对比卡马西平治疗非难治性复杂性癫痫发作的 PTS

• 批准号: 6274830
• 负责人: GREGORY Y CHANG
• 金额: $ 3.67万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6274830
• 关键词: anticonvulsants; brain disorder chemotherapy; carbamazepine; clinical research; clinical trials; combination chemotherapy; drug screening /evaluation; human subject; human therapy evaluation; partial seizure; phenytoin

The primary objective of this study is to determine the efficacy of Sabril as add-on therapy in non-refractory patients who experience occasional complex partial seizure while on carbarmazepine monotherapy. Specifically, the efficacy, safety and impact on quality of life of rational polytherapy with Sabril and carbamazepine, in comparison to monotherapy with carbamazepine, will be assessed.

本研究的主要目的是确定Sabril的疗效 作为非难治性患者的辅助治疗， 复杂部分性癫痫发作。 具体而言，研究了以下药物的疗效、安全性和对生活质量的影响： 合理的多药治疗与Sabril和卡马西平相比， 将评估卡马西平单药治疗。