SABRIL (VIGABATRIM) VS CARBAMAZEPINE IN PTS W/NON-REFRACTORY COMPLEX SEIZURES

SABRIL (VIGABATRIM) 对比卡马西平治疗非难治性复杂性癫痫发作的 PTS

• 批准号: 6244757
• 负责人: GREGORY Y CHANG
• 金额: $ 3.96万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-01-23 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6244757
• 关键词: anticonvulsants; brain disorder chemotherapy; carbamazepine; clinical research; clinical trials; combination chemotherapy; drug screening /evaluation; human subject; human therapy evaluation; partial seizure; phenytoin

The primary objective of this study is to determine the efficacy of Sabril as add-on therapy in non-refractory patients who experience occasional complex partial seizure while on carbarmazepine monotherapy. Specifically, the efficacy, safety and impact on quality of life of rational polytherapy with Sabril and carbamazepine, in comparison to monotherapy with carbamazepine, will be assessed.

这项研究的主要目的是确定 在经历了以下情况的非难治性患者的基础上加用沙普利 在接受卡马西平单一治疗时偶尔出现复杂的部分性发作。 具体地说，治疗的有效性、安全性和对生活质量的影响 与卡马西平、卡马西平合理综合治疗的比较 卡马西平的单一疗法，将得到评估。