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OUTCOME OF PATIENTS W/CONGENITAL HEART MALFORMATIONS FOLLOWING FONTAN PROCEDURE

OUTCOME OF PATIENTS W/CONGENITAL HEART MALFORMATIONS FOLLOWING FONTAN PROCEDURE
先天性心脏畸形患者接受 Fontan 手术后的结果
批准号：
6113463
负责人：
CAREN S GOLDBERG
金额：
$2.14万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/6113463
关键词：
central nervous system child (0-11) clinical research congenital heart disorder developmental neurobiology heart surgery human subject outcomes research physiologic stressor

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中文摘要
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英文摘要
OBJECTIVE: Evaluate the neurodevelopmental outcome (NDO) of patients with hypoplastic left heart synbdrome (HLHS) following surgical palliation. APPROACH: 1) Perform neurodevelopmental testing on HLHS patients; 2) Compare NDO of HLHS patients to NDO of healthy children and to NDO of patients with non-HLHS congenital heart lesions requiring a similar surgical approach; 3) Evaluate factors in these patients which may contribute to abnormal neurodevelopment including structural abnormalities of the central nervous system and perioperative stresses. SIGNIFICANCE: May impact future approach to treating patients with HLHS.
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Pediatric Heart Network Regents of the University of Michigan
Pediatric Heart Network Regents of the University of Michigan
Pediatric Heart Network Regents of the University of Michigan
Pediatric Heart Network Regents of the University of Michigan