AFRICAN AMERICAN STUDY OF KIDNEY DISEASE (AASK)

非裔美国人肾脏疾病研究 (AASK)

• 批准号: 6114287
• 负责人: LAWRENCE JOHN APPEL
• 金额: $ 2.06万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6114287
• 关键词: ACE inhibitors; African American; antihypertensive agents; beta antiadrenergic agent; calcium channel blockers; cardiovascular disorder chemotherapy; clinical research; clinical trials; drug screening /evaluation; human subject; human therapy evaluation; kidney disorder chemotherapy; kidney function; longitudinal human study; renal hypertension

This study is a randomized clinical trial that tests the impact of 2 different levels of blood pressure control (usual level versus lower level) and 3 different types of antihypertensive drug regimens (beta- blocker, calcium channel blocker, and angiotensin converting enzyme inhibitor) on renal function over 5 years of follow-up. The study population consists of African-American men and women with early evidence of hypertension-related kidney disease (GFR of 25-65 ml/min/M2) . The trial is in its recruitment phase. To date, 50 persons have enrolled.

这项研究是一项随机临床试验，测试了2的影响 不同水平的血压控制水平（通常水平与较低水平 水平）和3种不同类型的降压药方案（β- 阻滞剂，钙通道阻滞剂和血管紧张素转化酶 抑制剂）在5年的随访中肾功能。 研究 人口由早期的非裔美国人和女人组成 高血压相关肾脏疾病的证据（GFR为25-65 ml/min/m2）。该试验处于招聘阶段。 迄今为止，有50人 已经注册了。