Development of a novel orally active peptide for the treatment of pain

开发用于治疗疼痛的新型口服活性肽

• 批准号: nhmrc : 519822
• 负责人: Dr Richard Clark
• 金额: $ 26.82万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Development Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-novel-orally-treatment-pain/76155
• 关键词: Development; novel; orally; active; peptide

Chronic pain from damage to the nervous system is difficult to treat. A new type of drug has recently been developed from sea snail venom to treat chronic pain but is given by injection, which limits its use. Our research has developed a stable molecule that has analgesic activity when ingested. This proposal focuses on further testing to fully establish this molecule's therapeutic potential. This information can then attract a commercial partner to bring the new drug into general use.

神经系统损伤引起的慢性疼痛很难治疗。最近，利用海蜗牛毒液开发出了一种治疗慢性疼痛的新药，但由于只能注射，因此使用范围受到限制。我们的研究已经开发出一种稳定的分子，当摄入时具有镇痛活性。这项建议的重点是进一步的测试，以充分建立这种分子的治疗潜力。然后，这些信息可以吸引商业伙伴将新药投入普遍使用。