Understanding the structure/function relationships of the iron regulatory peptide hepcidin

该项目旨在了解多肽激素海普西丁及其受体之间的相互作用，并利用这些信息开发新药。海普西丁是人类主要的铁调节激素，一系列与铁有关的疾病是由这种激素水平错误引起的。许多澳大利亚人受到这些疾病的影响，因此基于海普西丁的治疗方法的发展有可能对社区的整体健康产生重大影响。

This project seeks to understand the interactions between the peptide hormone hepcidin and its receptor and use this information to develop new drugs. Hepcidin is the major iron-regulatory hormone in humans and a range of iron-related diseases are caused by incorrect levels of this hormone. Many Australians are affected by these diseases so the development of hepcidin-based treatments has the potential to have significant impact on the overall health of the community.