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RANDOMIZED, PLACEBO CONTROLLED, SINGLE DOSE STUDY OF INTRAVENOUS CVT 124

RANDOMIZED, PLACEBO CONTROLLED, SINGLE DOSE STUDY OF INTRAVENOUS CVT 124
静脉 CVT 的随机、安慰剂对照、单剂量研究 124
批准号：
6117843
负责人：
D CRAIG BRATER
金额：
$1.7万
依托单位：
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6117843
关键词：
clinical research congestive heart failure diuresis diuretics dosage drug adverse effect drug screening /evaluation electrolytes heart disorder chemotherapy human subject human therapy evaluation intravenous administration placebos urinalysis

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中文摘要
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英文摘要
The primary objective of this Phase II study is to test the diuretic efficacy of single intravenous doses of CVT-124 at three dose levels in patients with stable NYHA class II and III congestive heart (CHF) assessed by changes in electrolyte excretion, urine volumes, and weight. The secondary objective of this study is to assess the safety and tolerability of a single IV dose of CVT-124 at three dose levels in patients with stable CHF.
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Diuretics on Response to Torsemide in Patients with Congestive Heart Failure
General Clinical Research Ctr:Pharmacogenetics Core Supp
MULTICENTER DOUBLE BLIND PLACEBO CONTROLLED STUDY TO EVALUATE AND COMPARE
MULTICENTER DOUBLE BLIND PLACEBO CONTROLLED STUDY TO EVALUATE AND COMPARE
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