MULTICENTER DOUBLE BLIND PLACEBO CONTROLLED STUDY TO EVALUATE AND COMPARE
多中心双盲安慰剂对照研究的评估和比较
基本信息
- 批准号:6291013
- 负责人:
- 金额:$ 1.7万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1998
- 资助国家:美国
- 起止时间:1998-12-01 至 1999-11-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Nonsteroidal anti-inflammatory drugs (NSAIDs) are on of the most widely
prescribed class of medications. While generally safe, this class of
medications may be associated with serious gastrointestinal and renal
adverse effects, both there efficacy and toxicity is attributed to the
inhibition of cyclo-oxygenase (COX). Cyclo-oxygenase has recently been
discovered to exist in two isoforms COX-1 which is involved in maintenance
prostaglandins and COX-2 which is involved in the production of
inflammatory prostaglandins. Currently available nonsteroidal anti-
inflammatory drugs (NSAIDs) have been characterized as dual COX-1 and
COX-2 inhibitors [1,2]. This is a double-blind, placebo-controlled,
multicenter, double-dummy, parallel group study to evaluate and compare
the effects of multiple doses of the selective COX-2 inhibitor MK-0966,
indomethacin, and placebo on renal function in subjects 65 to 80 year of
age with creatinine clearance 30 to 80 ml/minute.
非甾体类抗炎药(NSAIDs)是应用最广泛的药物之一
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
D CRAIG BRATER其他文献
D CRAIG BRATER的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('D CRAIG BRATER', 18)}}的其他基金
Diuretics on Response to Torsemide in Patients with Congestive Heart Failure
利尿剂对充血性心力衰竭患者托拉塞米反应的影响
- 批准号:
7045166 - 财政年份:2003
- 资助金额:
$ 1.7万 - 项目类别:
General Clinical Research Ctr:Pharmacogenetics Core Supp
一般临床研究中心:药物遗传学核心补充
- 批准号:
6720085 - 财政年份:1999
- 资助金额:
$ 1.7万 - 项目类别:
MULTICENTER DOUBLE BLIND PLACEBO CONTROLLED STUDY TO EVALUATE AND COMPARE
多中心双盲安慰剂对照研究的评估和比较
- 批准号:
6117873 - 财政年份:1998
- 资助金额:
$ 1.7万 - 项目类别:
RANDOMIZED, PLACEBO CONTROLLED, SINGLE DOSE STUDY OF INTRAVENOUS CVT 124
静脉 CVT 的随机、安慰剂对照、单剂量研究 124
- 批准号:
6117843 - 财政年份:1998
- 资助金额:
$ 1.7万 - 项目类别:
MULTICENTER DOUBLE BLIND PLACEBO CONTROLLED STUDY TO EVALUATE AND COMPARE
多中心双盲安慰剂对照研究的评估和比较
- 批准号:
6291139 - 财政年份:1998
- 资助金额:
$ 1.7万 - 项目类别:
INTERACTION OF INTRAVENOUS DILTIAZEM WITH LOVASTATIN
静脉注射地尔硫卓与洛伐他汀的相互作用
- 批准号:
6291160 - 财政年份:1998
- 资助金额:
$ 1.7万 - 项目类别:
INTERACTION OF INTRAVENOUS DILTIAZEM WITH LOVASTATIN
静脉注射地尔硫卓与洛伐他汀的相互作用
- 批准号:
6117842 - 财政年份:1998
- 资助金额:
$ 1.7万 - 项目类别:
RANDOMIZED, PLACEBO CONTROLLED, SINGLE DOSE STUDY OF INTRAVENOUS CVT 124
静脉 CVT 的随机、安慰剂对照、单剂量研究 124
- 批准号:
6291035 - 财政年份:1998
- 资助金额:
$ 1.7万 - 项目类别:
CONTRIBUTION OF INTESTINAL CYP3A TO FIRST PASS METABOLISM OF MIDAZOLAM
肠道 CYP3A 对咪达唑仑首过代谢的贡献
- 批准号:
6117753 - 财政年份:1998
- 资助金额:
$ 1.7万 - 项目类别:
INTERACTION OF DILTIAZEM & VERAPAMIL WITH SIMVASTATIN
地尔硫卓的相互作用
- 批准号:
6265102 - 财政年份:1998
- 资助金额:
$ 1.7万 - 项目类别:
相似海外基金
The IDeA State Consortium for a Clinical Research Resource Center: Increasing Clinical Trials in IDeA States through Communication of Opportunities, Effective Marketing, and WorkforceDevelopment
IDeA 州临床研究资源中心联盟:通过机会交流、有效营销和劳动力发展增加 IDeA 州的临床试验
- 批准号:
10715568 - 财政年份:2023
- 资助金额:
$ 1.7万 - 项目类别:
CAPRISA CASCADE Clinical Trials Network Clinical Research Site
CAPRISA CASCADE 临床试验网络临床研究网站
- 批准号:
10754981 - 财政年份:2023
- 资助金额:
$ 1.7万 - 项目类别:
TO PROVIDE BIO-MEDICAL AND BEHAVIORAL RESEARCH RESOURCES AND CLINICAL RESEARCH COORDINATING SERVICES TO SUPPORT THE NIDA CLINICAL TRIALS NETWORK (CTN)
提供生物医学和行为研究资源以及临床研究协调服务以支持 NIDA 临床试验网络 (CTN)
- 批准号:
10617997 - 财政年份:2022
- 资助金额:
$ 1.7万 - 项目类别:
TO PROVIDE BIO-MEDICAL AND BEHAVIORAL RESEARCH RESOURCES AND CLINICAL RESEARCH COORDINATING SERVICES TO SUPPORT THE NIDA CLINICAL TRIALS NETWORK (CTN)
提供生物医学和行为研究资源以及临床研究协调服务以支持 NIDA 临床试验网络 (CTN)
- 批准号:
10538151 - 财政年份:2021
- 资助金额:
$ 1.7万 - 项目类别:
Admin. Supp. for NCI P30 Cancer Center Grants to Facilitate the Development of Standardized Electronic Treatment Plan Builds for NCI-Supported Clinical Trials Applicable Across Clinical Research Sites
行政。
- 批准号:
10442122 - 财政年份:2021
- 资助金额:
$ 1.7万 - 项目类别:
Health 360x Clinical Research Platform for Scalable Access to Clinical Trials
Health 360x 临床研究平台可扩展临床试验的访问
- 批准号:
10624966 - 财政年份:2021
- 资助金额:
$ 1.7万 - 项目类别:
Health 360x Clinical Research Platform for Scalable Access to Clinical Trials
Health 360x 临床研究平台可扩展临床试验的访问
- 批准号:
10515803 - 财政年份:2021
- 资助金额:
$ 1.7万 - 项目类别:
Health 360x Clinical Research Platform for Scalable Access to Clinical Trials
Health 360x 临床研究平台可扩展临床试验的访问
- 批准号:
10258627 - 财政年份:2021
- 资助金额:
$ 1.7万 - 项目类别:
New Mexico Clinical Trials Node: Clinical research and practice to address substance use in diverse, rural and underserved populations
新墨西哥州临床试验节点:解决多样化、农村和服务不足人群的药物使用问题的临床研究和实践
- 批准号:
10581505 - 财政年份:2019
- 资助金额:
$ 1.7万 - 项目类别:
New Mexico Clinical Trials Node: Clinical research and practice to address substance use in diverse, rural and underserved populations
新墨西哥州临床试验节点:解决多样化、农村和服务不足人群的药物使用问题的临床研究和实践
- 批准号:
10379715 - 财政年份:2019
- 资助金额:
$ 1.7万 - 项目类别: