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ACTG 358--ORAL INDINAVIR IN HIV PREGNANT WOMEN & INFANTS

ACTG 358--ORAL INDINAVIR IN HIV PREGNANT WOMEN & INFANTS
ACTG 358——艾滋病毒孕妇口服印地那韦
批准号：
6265185
负责人：
STEPHEN A SPECTOR
金额：
$1.15万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6265185
关键词：
AIDS therapy HIV infections antiviral agents blood chemistry clinical research clinical trial phase I combination chemotherapy drug screening /evaluation drug tolerance female human subject human therapy evaluation indinavir infant human (0-1 year) lamivudine newborn human (0-6 weeks) oral administration pediatric AIDS pediatric pharmacology pregnancy infection protease inhibitor virus replication zidovudine

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中文摘要
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英文摘要
To see if indinavir (a protease inhibitor-a type of anti-HIV drug that stops the virus from reproducing itself) when given with ZDV and 3TC to HIV-infected pregnant women and their newborns is able to be tolerated and is safe, to find the levels of the drugs in blood and to find what dose should be given to the newborns.
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