COMPARISON OF ANALGESICS IN POSTOPERATIVE ORTHOPEDIC SURGERY PATIENTS

骨科手术患者术后镇痛药的比较

• 批准号: 6118129
• 负责人: CLIFFORD W COLWELL
• 金额: $ 2.74万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6118129
• 关键词: analgesics; clinical research; drug screening /evaluation; human subject; human therapy evaluation; nonsteroidal antiinflammatory agent; orthopedics; pain; postoperative state; questionnaires

This study compares two doses of a new COX-2 selective nonsteroidal anti-inflammatory drug, SC-58635, with a standard analgesic agent, propoxyphene napsylate, and with a placebo for the control of postoperative pain in patients hospitalized for procedures on the hip and knee. The primary end point is relief of pain which will be assessed using a standard questionnaire at frequent intervals for the first day and less often for up to five days. Study has been completed and no data are available yet.

这项研究比较了两种剂量的新型COX-2选择性非类固醇抗炎药SC-58635与标准止痛剂丙氧酚萘磺酸盐，以及用于控制髋关节和膝盖手术住院患者术后疼痛的安慰剂。主要的终点是缓解疼痛，第一天将经常使用标准问卷进行评估，而最多五天则较少使用。研究已经完成，目前还没有数据。