INTRAOPERATIVE CHANGES IN SERUM GROWTH HORMONE LEVELS WITH ACROMEGALY

肢端肥大症术中血清生长激素水平的变化

• 批准号: 6118211
• 负责人: THOMAS N PAJEWSKI
• 金额: $ 3.03万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6118211
• 关键词: acromegaly; clinical research; endocrine surgery; human subject; human therapy evaluation; peptide hormone metabolism; pituitary disorders; pituitary neoplasms; postoperative state; somatotropin

Determining those patients with acromegaly who are completely cured following microsurgical resection of pituitary tumors from those who are incompletely cured has traditionally required prolonged post-operative follow-up. Intraoperative changes in serum growth hormone in patients undergoing transphenoidal microsurgery may help delineate sooner those patients in whom surgery was successful from those in whom further intervention is needed.

确定那些完全治愈的肢端肥大的患者 在对垂体肿瘤的显微外科切除术后 传统上，不完整的治愈需要延长术后术 后续。患者血清生长激素的术中变化 经过跨类化学显微外科手术可能会有助于尽快描述 手术成功的患者 需要干预。