INTRAOPERATIVE CHANGES IN SERUM ACTH AND CORTISOL LEVELS IN CUSHINGS DISEASE

库欣病患者血清促肾上腺皮质激素和皮质醇水平的术中变化

• 批准号: 6279420
• 负责人: THOMAS N PAJEWSKI
• 金额: $ 3.19万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6279420
• 关键词: Cushing's syndrome; adrenocorticotropic hormone; clinical research; cortisol; hormone regulation /control mechanism; human subject; human therapy evaluation; neoplasm /cancer surgery; pituitary neoplasms; postoperative state; preoperative state

Determining those patients with Cushing's disease who are completely cured following microsurgical resection of pituitary tumors from those who are incompletely cured has traditionally required prolonged post- operative follow-up. Intraoperative changes in serum ACTH and cortisol levels in patients undergoing transphenoidal microsurgery may help delineate sooner those patients in whom surgery was successful from those in whom further intervention is needed.

确定那些完全是库欣病的患者 从垂体肿瘤的微神经切除后治愈 传统上，谁没有完全治愈的人需要长时间的后 手术后续行动。 术中血清ACTH和皮质醇的变化 接受型型显微外科手术的患者的水平可能有助于 从 需要进一步干预的人。