山梨醇脱氢酶 3D 结构的测定-猫眼课题宝

山梨醇脱氢酶 3D 结构的测定

批准号：

6119540

负责人：

ZHONGMIN WANG

金额：

$0.0万

依托单位：

STANFORD UNIVERSITY

依托单位国家：

美国

项目类别：

财政年份：

1999

资助国家：

美国

项目状态：

已结题

起止时间：

1999-03-01 至 2000-04-14

来源：

https://reporter.nih.gov/project-details/6119540

关键词：

biomaterials proteins structural biology

项目摘要

项目成果

ZHONGMIN WANG的其他基金

相似基金

相关文献

中文摘要

翻译

点击翻译按钮获取中文摘要

英文摘要

Sorbitol dehydrogenase, also known as glucitol, polyol, or L-iditol dehydrogenase, catalyzes the oxidation of sorbitol to fructose with NAD as a cofactor. It has been detected in a wide variety of animals, plants and microorganisms. Impaired activity of SDH, resulting in accumulation of sorbitol within cells, has been implicated in the etology of cerebral edema and diabetic polyneuropathy. The structure information of sorbitol dehydrogenase could be used to design inhibitors and drugs.

期刊论文(0)

专著(0)

科研奖励(0)

会议论文