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Structural biology and therapeutic targeting of proteins involved in infection and immunity

Structural biology and therapeutic targeting of proteins involved in infection and immunity
感染和免疫相关蛋白质的结构生物学和治疗靶向
批准号:
nhmrc : GNT1110971
负责人:
Prof Bostjan Kobe
金额:
$75.33万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --

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中文摘要
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英文摘要
Structural biology plays an essential role in uncovering how proteins function at the molecular level, and further facilitates strategies to develop therapeutics targeting the diseases these proteins are involved in. In the proposed work, I will focus on bacterial virulence factors, to develop new antibiotics and vaccination strategies, and proteins involved in innate immunity pathways, to develop therapeutics against a number of associated disorders including chronic inflammatory diseases.
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Nanocrystal Electron Diffraction Facility
  • 批准号:
    LE230100145
  • 项目类别:
    Linkage Infrastructure, Equipment and Facilities
  • 资助金额:
    $75.31万
  • 财政年份:
    2023
  • 负责人:
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Structural basis of plant immune receptor signaling
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    2022
  • 负责人:
    Prof Bostjan Kobe
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Unifying mechanisms of innate immunity signaling in animals and plants
  • 批准号:
    FL180100109
  • 项目类别:
    Australian Laureate Fellowships
  • 资助金额:
    $195.52万
  • 财政年份:
    2019
  • 负责人:
    Prof Bostjan Kobe
  • 依托单位:
Molecular mechanisms of signalling by plant immune receptors
  • 批准号:
    DP190102526
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $37.8万
  • 财政年份:
    2019
  • 负责人:
    Prof Bostjan Kobe
  • 依托单位:
国内基金
海外基金
组蛋白乙酰化修饰ATG13激活自噬在牵张应力介导骨缝Gli1+干细胞成骨中的机制研究
  • 批准号:
    82370988
  • 项目类别:
    面上项目
  • 资助金额:
    48.00万元
  • 批准年份:
    2023
  • 负责人:
    经典
  • 依托单位:
Journal of Integrative Plant Biology
  • 批准号:
    31024801
  • 项目类别:
    专项基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2010
  • 负责人:
    贺萍
  • 依托单位:
Computational Methods for Analyzing Toponome Data