MRI: ASSESS PALLIDOTOMY LESION PLACEMENT & LOCALIZE POST OP PARKINSONS DISEASE

近年来，射频腹后路的使用 苍白球切开术（VVP）作为一种对症治疗的医学 帕金森病（PD）的难治性运动症状已经获得 广泛接受。 一些中心报告说， 控制禁用dyskineasias的改进，开/关 特发性PD患者的波动和其他运动症状a 综合征波动和其他运动症状的患者 特发性帕金森病 虽然普遍认为VPP是 对许多患者有帮助，结果在患者之间差异很大 以及执行该操作的中心。 一旦原因 变异性可能是由于病变位置和大小的差异。 1. 确定苍白球毁损术的位置和大小， 难治性帕金森病及其相关疾病的治疗 与临床结果。 2. 确定Talairach坐标如何预测解剖学病变 位置. 3. 为了确定病变变化的空间位置， 时间

In recent years the use of radio frequency ventroposterior pallidotomy (VVP) as a symptomatic treatment for the medically refractory motor symptoms of Parkinson's disease (PD) has been gaining widespread acceptance. A number of centers have reported significant improvements in controlling disabling dyskineasias, on/off fluctuations and other motor symptoms in patients with idiopathic PD a syndrome fluctuations and other motor symptoms in patients with idiopathic PD. Although there is a general agreement that VPP is helpful for many patients, results vary considerably between patients and centers performing the operation. Once reason for this variability is likely due to differences in lesion placement and size. 1. To determine the location and size of pallidotomy lesions in the treatment of medically intractable Parkinson's disease and correlate them with clinical outcome. 2. To determine how Talairach coordinates predict anatomical lesion location. 3. To determine the spatial location of changes in the lesion over time.