DEVELOPMENT OF EPR CATHETER PROBES FOR IN VIVO STUDIES

用于体内研究的 EPR 导管探针的开发

• 批准号: 6123401
• 负责人: TADEUSZ WALCZAK
• 金额: $ 2.6万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-15 至 1999-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6123401
• 关键词: Mammalia; bioengineering /biomedical engineering; biomedical equipment development; biomedical resource; building /facility design /renovation; gas; prosthesis; technology /technique

One of the most promising approaches for obtaining very high sensitivity from deep within the body is to use a catheter probe. New catheter probe resonators have been designed and improved with an extended length. Various paramagnetic materials have been also examined for use with these catheters and these have been optimized for sensitivity to oxygen and for maximal SNR. We are presently looking at different polymer coatings for application to surfaces of these probes for reasons of bio-compatibility and oxygen permeability.

最有希望的方法之一是获得非常高的 从体内深处敏感的是使用导管探头。新的 导管探头谐振器已经设计并改进了一种 延伸长度。各种顺磁性材料也已经被 检查了这些导管的使用情况，这些导管已经过优化 对氧气的敏感度和最大信噪比。我们目前正在 看不同的聚合物涂层在表面的应用 这些探头的原因在于生物相容性和透氧性。