RESEARCH TRAINING IN BIOMEDICAL STUDIES OF BONE

骨生物医学研究培训

• 批准号: 2801945
• 负责人: DAVID J BAYLINK
• 金额: $ 11.27万
• 依托单位: LOMA LINDA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-09-01 至 2004-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2801945
• 关键词: RESEARCH; TRAINING; BIOMEDICAL; STUDIES; BONE

The research area of the proposed training program is bone biology. The disciplines represented by our faculty include biochemistry, physiology, cell biology, molecular biology, clinical chemistry, pathology, virology, and clinical research. Our basic research facility includes 8,400-square foot of wet bench laboratory space, including a BL3 virology equipped. Our faculty total eleven in number, with two M.D.s, eight Ph.D.s and one M.D./Ph.D. One of the major strengths of our organization is that our entire faculty occupy in the same general laboratory area at this VA Medical Center, though they represent different disciplines at Loma Linda University. Moreover, this spatial arrangement leads to and facilitates collaborations among faculty of different disciplines. Our faculty are well funded, as indicted by the fact that we have four VA Merit Review grants, eight NIH grants, two other federally funded grants, five industry grants, and six seed money grants from Loma Linda University. Thus, we have adequate sources of funding for our trainees. The organizational aspect of our training program is highly structured in that we have frequent meetings, such as journal clubs and staff meetings, and we have annual trainee evaluations. On the other hand our program is flexible in that the trainees select their own research projects and frequently select projects with more than one preceptor and projects involving more than one discipline. Our eleven faculty propose 24 major projects for four predoctoral fellows and four postdoctoral fellows. These trainees will have the opportunity to chose those projects which best fit their interest and background. These projects range from clinical projects to highly technical molecular biology projects. Most of these projects are federally funded. We are requesting four predoctoral slots and four postdoctoral slots. We have an adequate number of applicants to fill these slots. For example, in the last year, the relevant departments (biochemistry, microbiology, and anatomy) have had more than 100 applications from predoctoral candidates and the Mineral Metabolism Laboratory has had over 200 postdoctoral candidate applications. One means by which to evaluate the success of a training program is by the subsequent performance of the trainees. Seven of the past eight trainees from our training grant are still in academia, either in faculty positions or in training (the other trainee is setting up a biotech business in his area of expertise). Finally, we anticipate that the proposed training program will not only provide superior training to young qualified scientists, but will also enrich the overall research program of this laboratory and improve our scientific productivity.

拟建培训项目的研究领域为骨生物学。我们的教师代表的学科包括生物化学、生理学、细胞生物学、分子生物学、临床化学、病理学、病毒学和临床研究。我们的基础研究设施包括8400平方英尺的湿台式实验室空间，包括BL3病毒学设备。我们共有11名教师，其中2名博士，8名博士和1名医学博士。我们组织的主要优势之一是我们所有的教师都在VA医疗中心的同一个综合实验室区域，尽管他们在洛马琳达大学代表不同的学科。此外，这种空间安排导致并促进了不同学科教师之间的合作。我们的教师资金充足，我们有四项VA绩效评估拨款，八项NIH拨款，两项其他联邦资助拨款，五项行业拨款，以及六项来自洛马琳达大学的种子基金拨款。因此，我们有足够的资金来源为我们的学员。我们培训计划的组织方面是高度结构化的，我们经常开会，比如期刊俱乐部和员工会议，我们每年都有实习生评估。另一方面，我们的项目是灵活的，学员选择自己的研究项目，经常选择项目有一个以上的导师和项目涉及多个学科。11名教师提出24项重大项目，招收4名博士前研究员和4名博士后。这些学员将有机会选择最符合他们兴趣和背景的项目。这些项目范围从临床项目到高技术分子生物学项目。这些项目大多是由联邦政府资助的。我们申请4个博士预科和4个博士后。我们有足够的申请者来填补这些空缺。例如，去年，相关部门（生物化学、微生物学、解剖学）有100多名博士生申请，矿物质代谢实验室有200多名博士后申请。评估培训项目是否成功的一个方法是看受训者的后续表现。过去获得培训资助的8名受训者中，有7名仍在学术界，要么担任教职，要么在接受培训（另一名受训者正在他的专业领域创办生物技术企业）。最后，我们期望，所提出的培训计划不仅可以为年轻的合格科学家提供优质的培训，而且可以丰富本实验室的整体研究计划，提高我们的科学生产力。