RESEARCH TRAINING IN BIOMEDICAL STUDIES OF BONE

骨生物医学研究培训

• 批准号: 6171806
• 负责人: DAVID J BAYLINK
• 金额: $ 11.41万
• 依托单位: LOMA LINDA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-09-01 至 2004-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6171806
• 关键词: RESEARCH; TRAINING; BIOMEDICAL; STUDIES; BONE

The research area of the proposed training program is bone biology. The disciplines represented by our faculty include biochemistry, physiology, cell biology, molecular biology, clinical chemistry, pathology, virology, and clinical research. Our basic research facility includes 8,400-square foot of wet bench laboratory space, including a BL3 virology equipped. Our faculty total eleven in number, with two M.D.s, eight Ph.D.s and one M.D./Ph.D. One of the major strengths of our organization is that our entire faculty occupy in the same general laboratory area at this VA Medical Center, though they represent different disciplines at Loma Linda University. Moreover, this spatial arrangement leads to and facilitates collaborations among faculty of different disciplines. Our faculty are well funded, as indicted by the fact that we have four VA Merit Review grants, eight NIH grants, two other federally funded grants, five industry grants, and six seed money grants from Loma Linda University. Thus, we have adequate sources of funding for our trainees. The organizational aspect of our training program is highly structured in that we have frequent meetings, such as journal clubs and staff meetings, and we have annual trainee evaluations. On the other hand our program is flexible in that the trainees select their own research projects and frequently select projects with more than one preceptor and projects involving more than one discipline. Our eleven faculty propose 24 major projects for four predoctoral fellows and four postdoctoral fellows. These trainees will have the opportunity to chose those projects which best fit their interest and background. These projects range from clinical projects to highly technical molecular biology projects. Most of these projects are federally funded. We are requesting four predoctoral slots and four postdoctoral slots. We have an adequate number of applicants to fill these slots. For example, in the last year, the relevant departments (biochemistry, microbiology, and anatomy) have had more than 100 applications from predoctoral candidates and the Mineral Metabolism Laboratory has had over 200 postdoctoral candidate applications. One means by which to evaluate the success of a training program is by the subsequent performance of the trainees. Seven of the past eight trainees from our training grant are still in academia, either in faculty positions or in training (the other trainee is setting up a biotech business in his area of expertise). Finally, we anticipate that the proposed training program will not only provide superior training to young qualified scientists, but will also enrich the overall research program of this laboratory and improve our scientific productivity.

拟议的培训计划的研究领域是骨生物学。我们的教师代表的学科包括生物化学、生理学、细胞生物学、分子生物学、临床化学、病理学、病毒学和临床研究。我们的基础研究设施包括8400平方英尺的湿工作台实验室空间，其中包括配备的BL3病毒学设备。我们共有11名教职员工，其中包括两名医学博士、八名博士和一名医学博士/博士。我们组织的主要优势之一是，我们的全体教职员工都在这个退伍军人医学中心的同一个普通实验室领域工作，尽管他们代表洛马林达大学的不同学科。此外，这种空间安排导致并促进了不同学科的教职员工之间的合作。我们的教职员工资金充足，这一事实表明，我们有四项VA功绩审查拨款，八项NIH拨款，两项其他联邦资助的拨款，五项行业拨款，以及六项来自洛玛琳达大学的种子基金拨款。因此，我们有足够的资金来源来资助我们的学员。我们培训计划的组织方面是高度结构化的，因为我们经常召开会议，如杂志俱乐部和员工会议，我们还会进行年度实习生评估。另一方面，我们的计划是灵活的，因为受训人员选择自己的研究项目，并经常选择有多个导师的项目和涉及多个学科的项目。我们的11名教员为4名博士后研究员和4名博士后研究员提出了24个主要项目。这些学员将有机会选择最符合他们兴趣和背景的项目。这些项目的范围从临床项目到高技术的分子生物学项目。这些项目中的大多数是由联邦政府资助的。我们申请四个博士后名额和四个博士后名额。我们有足够数量的申请者来填补这些空缺。例如，去年，相关系(生物化学、微生物学、解剖学)收到了100多份博士后申请，矿物代谢实验室收到了200多份博士后申请。评估培训计划成功的一种方法是通过受训者随后的表现来评估。在我们过去的8名培训生中，有7人仍在学术界工作，要么是教员，要么是培训生(另一名实习生在他的专业领域创办了一家生物技术公司)。最后，我们预计，拟议的培训计划不仅将为合格的年轻科学家提供卓越的培训，还将丰富该实验室的整体研究计划，提高我们的科学生产率。