CLINICAL CENTERS FOR FEASIBILITY STUDIES ON RETINOID TRE

维甲酸 TRE 可行性研究临床中心

• 批准号: 6191636
• 负责人: JOE WESLEY RAMSDELL
• 金额: $ 10.05万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2002-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6191636
• 关键词: clinical research; clinical trials; drug administration rate /duration; emphysema; experimental designs; health science research analysis /evaluation; human subject; human therapy evaluation; nutrition related tag; outcomes research; patient /disease registry; respiratory disorder chemotherapy; retinoate; vitamin therapy

The overall objective of the Feasibility of Retinoic Acid Treatment in Emphysema (FORTE) study is to conduct preliminary studies at 5 clinical centers preparatory to conducting a randomized, controlled, clinical trial on the efficacy of retinoic acid therapy in the management of emphysema. Objectives are to identify optimal patient populations, drugs and dosing schedules, and outcome measures for a large study, if indicated. This project serves as a clinical center for the study.

维甲酸治疗肺气肿的可行性（FORTE）研究的总体目标是在5个临床中心进行初步研究，准备进行一项关于维甲酸治疗肺气肿疗效的随机对照临床试验。目标是确定最佳的患者人群，药物和给药方案，以及大型研究的结局指标（如有指征）。本项目作为本研究的临床中心。