SHORT-TERM TRAINING FOR MINORITY STUDENTS

这项建议是对国家心肺和血液研究所的及时倡议的回应，该倡议旨在增加心血管疾病研究中代表性不足的少数群体的数量。拟议的培训将在不同的心血管疾病研究领域接触、培训和指导少数民族学生。心血管疾病是美国人口死亡的主要原因，每年夺走超过98万人的生命，少数族裔尤其是非裔美国人受到的影响更大。该提案寻求通过招募有才华的少数族裔学生以及在侧重于心血管实验治疗学和药理学的研究项目中对有才华的少数族裔学生进行强化培训和指导，来解决少数族裔代表不足的问题。药学院将利用其在NIH资助的夏季少数民族生物医学研究实习计划中的丰富经验，该计划已连续实施三年(1995-1998年)，以增加进入生物医学科学职业生涯的少数民族。每年，在总共五年的时间里，八(8)名在大学至少呆过一年的少数族裔本科生将被招募到密西西比大学药学院药物化学和药理学系的心血管研究项目中。这些学员将在NIH、美国心脏协会和其他资助的研究项目中度过三个夏季月的培训，培训内容包括肾上腺素能受体药理学、α和β肾上腺素能受体特异性激动剂和拮抗剂的生化机制、新型腺苷转运阻滞剂的设计、一氧化氮合酶和补体系统抑制剂的设计，以防止缺血/再灌注损伤和/或心脏异种移植排斥反应。将采取积极的步骤，通过导师鼓励和建议、实地考察、特邀演讲者研讨会和/或榜样以及海报会议，激发学员对心血管研究的兴趣，并引导他们追求心血管研究的职业生涯。将制定计划，跟踪受训人员，以评估该计划的成功，并在认为必要时实施变化。招聘将在密西西比州的社区学院和大学进行。将与支线机构建立联系和直接联系，建立在已经建立的强大网络的基础上，比如密西西比少数人参与联盟，密西西比大学是该联盟的成员。该计划将在每个培训期间和之后通过广泛的调查进行评估。将向学生和导师发放调查问卷。参与者将被跟踪10年以评估计划。

This proposal responds to the timely initiative of the National Heart Lung and Blood Institute to increase the number of underrepresented minorities in cardiovascular disease research. the proposed training will be expose, train and mentor minority students in various cardiovascular disease research areas. cardiovascular disease is the number cause of death among the American population, taking the lives of over 980,000 people a year, minorities being disproportionately affected, especially African-Americans. The proposal seeks to address the problem of minority underrepresentation through both the recruitment, and intensive training and mentoring of talented minority students in research projects that are focused on cardiovascular experimental therapeutics, and pharmacology. The School of Pharmacy will draw from its extensive experience in the NIH-funded Summer Minority Biomedical Research Internship Program, which has been in place for three consecutive years (1995-1998), to increase the pool of minorities entering into careers in the biomedical sciences. Each year, for a total of five years, eight (8) minority undergraduate students who have spent at least one year in college, will be recruited into the cardiovascular research programs at the University of Mississippi School of Pharmacy, in the Department of Medicinal Chemistry and Pharmacology. These trainees will spend three summer months immersed in training under a faculty mentor, on NIH, American Heart Association, and other funded research projects in adrenergic receptor pharmacology, biochemical mechanisms of alpha- and beta-adrenergic receptor specific agonists and antagonists, the design of novel adenosine transport blockers, nitric oxide synthase and complement system inhibitors for prevention of ischemia/reperfusion injury and/or cardiac xenograft rejection. Proactive steps will be taken to create interest in, and guide trainees to pursue careers in cardiovascular research through mentor encouragement and advising, field trips, invited speakers seminars and/or role models, and poster sessions. Plans will be put in place to track trainees to evaluate the program's success, and to effect changes as deemed necessary. Recruitment will be in- state, from community colleges and universities in Mississippi. Liaisons and direct contacts will be established with feeder institutions, building on already established strong networks like the Mississippi Alliance for Minority Participation of which the University of Mississippi is a member. The program will be evaluated by extensive surveys during and after each training period. Students and mentors will be given questionnaire. Participants will be tracked for 10 years to assess program.