课题基金 / 基金详情

CORE--PREPARATION, STORAGE, AND SHIPPING OF PLANT EXTRACTS AND ASSAYS

CORE--PREPARATION, STORAGE, AND SHIPPING OF PLANT EXTRACTS AND ASSAYS
核心——植物提取物和检测的制备、储存和运输
批准号：
6352742
负责人：
Sidney Michael Hecht
金额：
$14.83万
依托单位：
UNIVERSITY OF VIRGINIA
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-07-01 至 2000-09-29
来源：
https://reporter.nih.gov/project-details/6352742
关键词：
DNA damage DNA directed DNA polymerase DNA topoisomerases antineoplastics chromatography drug screening /evaluation enzyme inhibitors plant extracts preservation

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Sidney Michael Hecht的其他基金

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中文摘要
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英文摘要
This Core facility will be responsible for carrying out the preparation, storage and shipping of plant extracts, and much of the assay work run within the NPDDG. This is to include . soaking of plant materials; weighing, packaging, shipping and inventorying of plant extracts . testing of extracts for the presence of DNA damaging agents, DNA topoisomerase inhibitors and DNA polymerase beta inhibitors, in support of Programs 2. . isolation of purified DNA topoisomerase I and DNA polymerase beta for assay work . screening of samples received from NCI natural products repository . guiding the choice of extracts by the development/application of secondary discrimination assays in support of Laboratory Programs 2 . guiding the fractionation of extracts within Laboratory Program 3
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