NURSING MEASUREMENT OF LYMPHEDEMATOUS LIMBS

描述：乳腺癌的治疗是导致淋巴水肿的主要原因。 美国。200万患有乳腺癌的女性面临罹患乳腺癌的风险 一生中的淋巴浮肿。淋巴水肿的不精确测量是一种 对与疾病相关的风险因素进行严格研究的主要威慑 淋巴水肿的发生和治疗效果。这项研究建议 评估和比较两种最先进的肢体体积测量方法与 40例乳腺癌后淋巴水肿妇女的“金标准”测评 治疗。主要的具体目标是评估信度、效度、 两种肢体体积测量的敏感性和实用性(序贯 圆周肢体测量和红外激光测量 将水排量作为“黄金标准”来衡量。一个 第二个目标是评估和比较生理参数(组织 氧合作用和皮肤温度)在患臂和非患臂。这些目标 将通过实验室评估(顺序肢体)完成 周长、周长和排水量)在两个时间点 每名受试者在同一天间隔4小时。两个测量值分别为 设计了不同的时间点来评估和比较 捕捉肢体体积随时间变化的3种模式。调查结果将 指导选择可靠、有效、灵敏、实用的测量方法 轻至重度淋巴水肿及变化的护理评估方案 时间到了。这项工作的顺利完成将为护理工作奠定基础 研究旨在1)测试有针对性的干预措施的有效性 预防、控制或解决乳腺癌治疗后继发的淋巴水肿， 以及2)测试干预措施的有效性，以实现其他相关 对乳房女性的生活质量很重要的结果 癌症。

DESCRIPTION: Breast cancer treatment is the leading cause of lymphedema in the United States. Two million women with breast cancer are at risk to develop lymphedema during their lifetimes. Imprecise measurement of lymphedema is a major deterrent to rigorous research on risk factors associated with the development of lymphedema and treatment efficacy. This study proposes to evaluate and compare two state of the art measures of limb volume compared to a "gold standard" measure in 40 women with lymphedema following breast cancer treatment. The primary specific aim is to assess the reliability, validity, sensitivity, and practicality of two measures of limb volume (sequential circumferential limb measurement and infrared laser measurement with the perometer) compared to water displacement as the "gold standard" measure. A secondary aim is to assess and compare physiological parameters (tissue oxygenation and skin temperature) in affected and non-affected arms. These aims will be accomplished through laboratory assessments (sequential limb circumferences, perometry, and water displacement) at two points in time with a 4-hour interval on the same day for each subject. The two measurements at different points in time are designed to assess and compare the sensitivity of the 3 modalities to capture changes in limb volume over time. Findings will guide the selection of a reliable, valid, sensitive, and practical measurement protocol for nursing assessment of mild to severe lymphedema and changes over time. Successful completion of this work will lay the foundation for a nursing study aimed at 1) testing the effectiveness of targeted interventions to prevent, control, or resolve lymphedema secondary to breast cancer treatment, and 2) testing the effectiveness of interventions to achieve other associated outcomes that are important for the quality of life of women with breast cancer.