Developmental Switches in Spermatogenesis

精子发生的发育开关

• 批准号: nhmrc : 1079646
• 负责人: Prof Katherine Loveland
• 金额: $ 47.04万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/developmental-switches-spermatogenesis/518683
• 关键词: Developmental; Switches; Spermatogenesis

I seek the knowledge required to improve prevention, diagnosis and therapy for men with testicular pathologies by studying what controls early sperm development. My research will delineate how cellular signalling molecules lay the foundation for adult fertility, using animal studies, cell culture and clinical samples. Testis samples from testicular cancer patients will be used to test interventions that may kill tumour cells or offer a therapeutic option to men with impaired spermatogenesis.

我寻求所需的知识，以改善预防，诊断和治疗男性睾丸病理通过研究什么控制早期精子发育。我的研究将通过动物研究、细胞培养和临床样本来描述细胞信号分子如何为成人生育能力奠定基础。来自睾丸癌患者的睾丸样本将用于测试可能杀死肿瘤细胞或为精子发生受损的男性提供治疗选择的干预措施。