Developmental Switches in Spermatogenesis

我通过研究控制早期精子发育的因素，寻求改善男性睾丸病变的预防、诊断和治疗所需的知识。我的研究将利用动物研究、细胞培养和临床样本来描绘细胞信号分子如何为成年生育奠定基础。来自睾丸癌患者的睾丸样本将被用来测试可能杀死肿瘤细胞的干预措施，或者为精子发生受损的男性提供治疗选择。

I seek the knowledge required to improve prevention, diagnosis and therapy for men with testicular pathologies by studying what controls early sperm development. My research will delineate how cellular signalling molecules lay the foundation for adult fertility, using animal studies, cell culture and clinical samples. Testis samples from testicular cancer patients will be used to test interventions that may kill tumour cells or offer a therapeutic option to men with impaired spermatogenesis.