CONSULTATION IN BIOSTATISTICAL METHODOLOGY AND CANCER CONTROL

生物统计方法学和癌症控制咨询

• 批准号: 6161610
• 负责人: C C BROWN
• 金额: --
• 依托单位: DIVISION OF CANCER PREVENTION AND CONTROL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6161610
• 关键词: breast neoplasms; cancer information system; cancer prevention; cancer risk; cervix neoplasms; chemoprevention; clinical research; colon neoplasms; data collection methodology /evaluation; dietary fiber; dietary lipid; folate; fruit; human data; information dissemination; neoplasm /cancer epidemiology; nutrition aspect of cancer; nutrition related tag; prostate neoplasms; selenium; statistical service /center; statistics /biometry; vegetables

The purpose of this project is to provide independent consultation to researchers within the NCI on problems related to biostatistical methodology and cancer control. Current projects include: - in collaboration with the Cancer Prevention Studies Branch, the American Association of Retired Persons (AARP) Observational Cohort Study has entered its third year. During the past year, a cohort of AARP members was created to investigate the relationship between their current dietary intake and their future incidence of cancer of the breast, colon/rectum, and prostate the internal calibration study has been constructed that includes about 2,000 members of the full cohort; and the 24-hour diet recalls and the second food frequency questionnaire (FFQ) were obtained for the subjects of the calibration study. Analysis of the calibration study has begun, which will allow us to evaluate the FFQ measurement errors and to correct the results of the main study for this error. - in collaboration with the Cancer Prevention Studies Branch, we completed research projects on 1) dietary folate intake and colorectal cancer and 2) the effects of dietary fat and fiber intake on androgen and estrogen levels in men. - in collaboration with the Cancer Prevention Studies Branch and the Applied Research Branch, a newly developed FFQ is being evaluated; over 600 participants were enrolled in a study using a daily checklist of selected foods to evaluate the food frequency accuracies of a sample of questionnaire items. - in collaboration with the Prevention and Control Extramural Branch, the Section provides consultation on the analysis and evaluation of the 5 A Day Program -- NCI's campaign to increase fruit and vegetable consumption. - in collaboration with the Applied Research Branch and the Environmental Epidemiology Branch, DCEG, the relationship between selenium status and cervical cancer is being investigated.

该项目的目的是提供独立咨询 NCI 内的研究人员研究与生物统计相关的问题 方法和癌症控制。目前的项目包括： - 与癌症预防研究处合作， 美国退休人员协会 (AARP) 观察队列研究 已进入第三个年头。在过去的一年里，美国退休人员协会 (AARP) 的一群人 成员的创建是为了调查他们当前之间的关系 饮食摄入量及其未来乳腺癌的发病率， 结肠/直肠和前列腺内部校准研究已 构建了包含约 2,000 名完整队列成员的结构；和 24小时饮食回忆和第二次食物频率调查问卷（FFQ） 为校准研究的受试者获得。分析 校准研究已经开始，这将使我们能够评估 FFQ 测量误差并纠正本次主要研究的结果 错误。 - 与癌症预防研究处合作，我们 完成了以下方面的研究项目：1) 膳食叶酸摄入量与结直肠癌 癌症和 2) 膳食脂肪和纤维摄入量对雄激素和 男性的雌激素水平。 - 与癌症预防研究处和 应用研究分支，新开发的FFQ正在评估中；超过 600 名参与者参加了一项研究，使用每日清单 选择食物来评估样本的食物频率准确性 问卷项目。 - 与校外防控部门合作， 部分提供对5A的分析和评估的咨询 日间计划——NCI 增加水果和蔬菜的活动 消耗。 - 与应用研究部门和环境部门合作 DCEG流行病学分会，硒状况与 宫颈癌正在接受调查。