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BONE LOSS IN THE ORAL CAVITY AND ITS RELATION TO SKELETAL BONE HEALTH

BONE LOSS IN THE ORAL CAVITY AND ITS RELATION TO SKELETAL BONE HEALTH
口腔骨质流失及其与骨骼健康的关系
批准号:
6161827
负责人:
H C GIFT
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:

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中文摘要
翻译
口腔中的骨质流失是美国的一个重要问题, States. 在齿状,口腔骨损失可能表现为牙齿的损失 支持. 在缺齿个体中,骨质减少可能增加局部解剖, 生物和机械因素导致广泛的嵴萎缩。 在医学和牙科文献中有这样的推测, 全身性骨骼骨量减少可能有助于加速丧失 口骨 因此,骨骼骨量减少可能会影响对 牙周、修复前和种植手术的结果。 本研究的目的是描述口腔骨量的变化 和质量与年龄的关系,以及与健康和 疾病 根据雅阁目的, 指定的骨密度中心必须招募1000名绝经期和绝经后妇女, 参加妇女健康方案观察部分的妇女 倡议(WHI)。 在基线和3年间隔时,由 WHI研究方案,参与者将接受全面的口腔检查, 包括后牙的标准化X光片或相应的 无齿间隙 自我护理的临时信息将通过以下方式获得: 询问参与者及其牙科提供者将被要求提供 每年更新患者记录。 来自口腔部分的数据正在 链接到WHI参与者的文件,从而建立框架 用于描述性和分析性分析牙齿和口腔骨状况, 与健康行为、医疗状况和骨骼骨密度的关系 评估。 截至1996年12月,已有240名学员接受了培训, 基线检查。 使用数据进行初步横断面分析 从前160名参与者表明, 通过口内X线片和髋骨测量的基础骨密度 矿物密度这是一个主要的假设正在测试中, study.
英文摘要
Bone loss in the oral cavity is a significant problem in the United States. In the dentate, oral bone loss may manifest as a loss of tooth support. In edentate individuals, osteopenia may augment local anatomic, biological, and mechanical factors resulting in extensive ridge atrophy. There have been speculations in the medical and dental literature that generalized skeletal osteopenia may be conducive to accelerated loss of oral bone. Thus, skeletal osteopenia may influence the need for and outcome of periodontal, pre-prosthetic, and implant surgical procedures. The objective of this research is to describe changes in oral bone mass and quality with age and in relation to skeletal bone status in health and disease. In accord with the research objectives, investigators from a designated Bone Density Center must recruit 1000 peri- and post-menopausal women enrolled in the observational component of the Women's Health Initiative (WHI). At baseline and at 3-year intervals as dictated by the WHI study protocol, participants will receive a thorough oral examination, including standardized radiographs of the posterior teeth or corresponding edentulous spaces. Interim information on self-care will be obtained by querying participants and their dental providers will be asked to provide yearly updates of patient records. Data from the oral component is being linked to the WHI participant's file thereby establishing the framework for descriptive and analytic analyses of tooth and oral bone status in relation to health behaviors, medical status, and skeletal bone density assessments. As of December 1996, 240 participants have undergone baseline examinations. Preliminary cross-sectional analysis using data from the first 160 participants indicate a significant association between basal bone density as measured from intraoral radiographs and hip bone mineral density. This is one of the major hypotheses being tested in this study.
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