ASSESSMENT OF SALIVA AS A MATRIX FOR THE BIOCHEMICAL VALIDATION OF FAT INTAKE

近年来，流行病学家和其他医学研究人员已经成为 越来越多的人对饮食可能对健康和 疾病。研究糖尿病营养病因的主要障碍是 疾病一直不确定现有饮食的有效性 评估方法及其结果的不确定性 从他们那里得到的。唾液法测定脂肪摄入量 分析提供了一种比传统方法更具吸引力的替代方法 要么是主观的，要么是侵入性的。沿着这条线取得积极成果 调查性研究将有助于进行有效和有用的 研究各种慢性病，包括癌症和心脏病。 目前正在分析数据，以便进行这项前瞻性研究，探索 唾液脂肪谱作为更传统的辅助工具的应用 参加《妇女健康》的妇女的膳食评估方法 试验(WHT)在少数民族人群中的可行性研究。学习志愿者 在中心研究中进行了跟踪，但除此之外，还捐赠了 基线、3个月、6个月随访。收集到的唾液样本 储存并运往德克萨斯A&M的分析实验室 大学的血脂分析专家。 截至1997年7月，所有脂类分析均已完成。数据来自 唾液成分目前正在与来自 妇女健康试验，以评估 唾液脂类、血脂、饮食摄入量等相关数据 变量。

In recent years epidemiologists and other medical researchers have become increasingly interested in the effects that diet may have on health and disease. The chief impediment to research on nutritional causes of disease has been uncertainty about the validity of existing dietary assessment methods and the consequent uncertainty about the results obtained from them. Ascertainment of fat intake by means of salivary analyses affords an attractive alternative to more conventional procedures that are either subjective or invasive. Positive outcomes along this line of investigative research will facilitate the conduct of valid and useful research on various chronic diseases, including cancer and heart disease. Data are currently being analyzed for this prospective study exploring the utility of salivary lipid profiles as an adjunct to more traditional dietary assessment methods among women enrolled in the Women's Health Trial (WHT) Feasibility Study in Minority Populations. Study volunteers were followed in the central study but in addition donated saliva at baseline, 3 month and 6 month follow-up. The collected saliva specimens were stored and shipped to the analytic laboratory at Texas A & M University for lipid analyses. As of July 1997 all lipid analyses had been completed. Data from the salivary component presently are being collated with pertinent data from the Women's Health Trial in order to evaluate the associations among salivary lipids, blood lipids, dietary intake data, and other pertinent variables.