CORE--ANIMAL FACILITY

核心——动物设施

• 批准号: 6340707
• 负责人: MARY P Corr
• 金额: $ 12.62万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6340707
• 关键词: animal colony; biomedical facility; laboratory mouse

Intradermal gene vaccination of rodents with naked plasmid DNA (pDNA) has been previously shown to deviate an ongoing Th2 mediated IgE response to a predominately Th1 response. In order to test further refined vaccination strategies and elucidate the cellular mechanisms involved in t his phenomenon individual investigators have proposed extensive rodent studies. Therefore an Animal Core will be established to 1) breed and provide sufficient number of mice from strains that are not commmerically available to individual investigators, 2) routinely provide technical assistance to the investigators with ear punching, bleeding and injecting mice, and 3) provide service to scientific investigators by assisting with animal care, drug administratioin and special procedures.

裸鼠质粒DNA皮内基因接种