Animal Models and Care

动物模型和护理

• 批准号: 7490291
• 负责人: MARY P Corr
• 金额: $ 6.41万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7490291
• 关键词: Amendment; Animal Model; Animals; Arts; Cancer Center; Caring; Clinical; Educational process of instructing; Environmental Health; Experimental Designs; Housing; Human Resources; Image; Imaging technology; Modeling; Mus; Oryctolagus cuniculus; Preparation; Procedures; Protocols documentation; Research Personnel; Resources; Safety; Time; Work; human disease; in vivo Cellular and Molecular Imaging Centers; programs; skills

The rapidly developing advancements in modern imaging technology requires ever more sophisticated animal models. This lends to cooperative efforts between experts in imaging and those with specialized skills in modeling human disease in animals. Hence an Animal Model and Care Core with expertise in a variety of animal models, procedures and husbandry will add to the overall synergy of the program. The Core aims to i) provide advice and expertise in experimental design, ii) assist in the preparation of animal protocols and amendments and coordinate with Environmental Health and Safety when appropriate, iii) streamline the acquisition and transfer of animals, and iv) provide procedural assistance as needed. The two main species in the ICMIC are mice and rabbits. To accomodate this need the work with mice will be coordinated at the John and Rebecca Moores Comprehensive UCSD Cancer Center. This new building has a state of the art vivarium that is located on the same level as the Small Animal Imaging Resource. The proximity of these two vital functions enhances the synergy to optimize the timing of the imaging in the sophisticated models. The rabbits will be housed in the Clinical Teaching Facility. The personnel of the Core will be able to provide assistance to the investigators that are using each of these facilities.

现代成像技术的快速发展需要更加复杂的 动物模型这有助于成像专家和具有专门技能的人之间的合作努力 在动物身上模拟人类疾病因此，一个动物模型和护理核心具有各种专业知识， 动物模型、程序和饲养将增加该计划的整体协同作用。核心旨在 i）提供实验设计方面的建议和专业知识，ii）协助编写动物方案， 修订并在适当时与环境健康和安全协调，iii）简化 动物的获取和转移，以及iv）根据需要提供程序援助。两个主要物种 在ICMIC中的是小鼠和兔子。为了适应这一需要，将在 约翰和丽贝卡摩尔综合UCSD癌症中心。这座新建筑物具有最先进的技术水平 与小动物影像资源位于同一楼层的动物园。这两个人的接近 重要功能增强了协同作用，以优化复杂模型中的成像时间。的 将家兔圈养在临床教学设施中。核心的人员将能够提供 协助正在使用这些设施的调查人员。