FOLLOW-UP STUDY OF EARLY CHILDHOOD CARIES

幼儿期龋齿的随访研究

• 批准号: 6203916
• 负责人: ROBERT J BERKOWITZ
• 金额: $ 3.99万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-15 至 2002-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6203916
• 关键词: Streptococcus mutans; attitude; clinical research; clinical trials; dental caries; dental disorder chemotherapy; dental health education; disease /disorder proneness /risk; epidemiology; family genetics; gene environment interaction; human subject; human therapy evaluation; ingested fluoride therapy; interview; longitudinal human study; medical rehabilitation related tag; oral bacteria; oral health; outcomes research; preschool child (1-5); questionnaires; racial /ethnic difference; saliva

This is the second resubmission of application which is an investigation of clinical outcomes for 80 patients treated for Early Childhood Caries (ECC). In the proposed descriptive study, clinical outcomes are defined in terms of longitudinal oral health, at an exam at six and twelve months after treatment for ECC. No further clinical caries and low levels of mutans streptococci at the post-treatment examination will constitute a positive clinical outcome. Negative outcomes will include high mutans streptococci level with no further decay, and further decay regardless of mutants streptococci level. These measures go beyond the usual definition of successful restorative treatment both temporally, by including follow-ups status and qualitatively, by incorporating measures of mutans streptococci, an etiologic component of ECC. The project will describe patterns related to positive and negative clinical outcomes to epidemiological perspective using data derived from a questionnaire that will be administered in an interview setting. Patients who have had ECC treatment will be described in terms of: a) extent of caries present and oral mutans streptococci level (this defines whether the outcome is positive or negative); b) behaviors: successful cessation of bottle use, fluoride use and frequency of snacking, child's sleep patterns, temperament; c) parental factors: dental knowledge, attitudes and self-described oral health, education level, ethnic identity, daycare arrangements, attitude toward trying to make changes or assume new responsibilities. This research is intended as a pilot study to generate further hypotheses.

这是第二次重新提交申请 对 80 名儿童早期治疗患者的临床结果的调查 龋齿（ECC）。在拟议的描述性研究中，定义了临床结果 就纵向口腔健康而言，在六个月和十二个月后进行的检查 ECC 的治疗。没有进一步的临床龋齿和低水平的变异 治疗后检查中的链球菌将构成阳性 临床结果。负面结果将包括高变形链球菌水平 没有进一步腐烂，并且无论突变链球菌如何，都会进一步腐烂 等级。这些措施超出了成功恢复的通常定义 治疗包括时间性治疗（包括随访状态）和质量治疗（包括随访状态） 纳入变形链球菌的测量，变形链球菌是 ECC 的病因之一。 该项目将描述与阳性和阴性临床相关的模式 使用问卷调查数据得出流行病学观点的结果 这将在面试环境中进行。患有 ECC 的患者 治疗将根据以下方面进行描述： a) 存在龋齿的程度和口腔 变形链球菌水平（这定义了结果是阳性还是 消极的）; b) 行为：成功停止使用奶瓶、使用氟化物和 吃零食的频率、孩子的睡眠模式、性格； c) 父母的 因素：牙科知识、态度和自我描述的口腔健康、教育 水平、种族认同、日托安排、对努力的态度 改变或承担新的责任。这项研究旨在作为试点 研究产生进一步的假设。