FOLLOW-UP STUDY OF EARLY CHILDHOOD CARIES

幼儿期龋齿的随访研究

• 批准号: 6379880
• 负责人: ROBERT J BERKOWITZ
• 金额: $ 3.99万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-15 至 2003-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6379880
• 关键词: Streptococcus mutans; attitude; clinical research; clinical trials; dental caries; dental disorder chemotherapy; dental health education; disease /disorder proneness /risk; epidemiology; family genetics; gene environment interaction; human subject; human therapy evaluation; ingested fluoride therapy; interview; longitudinal human study; medical rehabilitation related tag; oral bacteria; oral health; outcomes research; preschool child (1-5); questionnaires; racial /ethnic difference; saliva

This is the second resubmission of application which is an investigation of clinical outcomes for 80 patients treated for Early Childhood Caries (ECC). In the proposed descriptive study, clinical outcomes are defined in terms of longitudinal oral health, at an exam at six and twelve months after treatment for ECC. No further clinical caries and low levels of mutans streptococci at the post-treatment examination will constitute a positive clinical outcome. Negative outcomes will include high mutans streptococci level with no further decay, and further decay regardless of mutants streptococci level. These measures go beyond the usual definition of successful restorative treatment both temporally, by including follow-ups status and qualitatively, by incorporating measures of mutans streptococci, an etiologic component of ECC. The project will describe patterns related to positive and negative clinical outcomes to epidemiological perspective using data derived from a questionnaire that will be administered in an interview setting. Patients who have had ECC treatment will be described in terms of: a) extent of caries present and oral mutans streptococci level (this defines whether the outcome is positive or negative); b) behaviors: successful cessation of bottle use, fluoride use and frequency of snacking, child's sleep patterns, temperament; c) parental factors: dental knowledge, attitudes and self-described oral health, education level, ethnic identity, daycare arrangements, attitude toward trying to make changes or assume new responsibilities. This research is intended as a pilot study to generate further hypotheses.

这是第二次重新提交申请，这是一个 80例儿童早期疾病的临床疗效调查 龋病(ECC)。在拟议的描述性研究中，定义了临床结果 在纵向口腔健康方面，在6个月和12个月后的检查中 ECC的治疗。没有进一步的临床龋齿和低水平的变种 链球菌在治疗后的检查中将构成阳性 临床结果。阴性结果将包括高水平的变形链球菌 不再有进一步的腐烂，而不考虑突变的链球菌 水平。这些措施超出了成功恢复性的通常定义 通过包括随访状态和质量，在时间上和质量上，通过 纳入变形链球菌的措施，变形链球菌是ECC的病原学成分。 该项目将描述与阳性和阴性临床相关的模式。 使用来自调查问卷的数据对流行病学观点的结果 这将在面试环境中进行。患有ECC的患者 治疗将从以下方面进行描述：a)存在的龋齿和口腔龋齿的程度 变形链球菌水平(这定义了结果是阳性还是 否定)；b)行为：成功停止使用瓶子、使用氟和 吃零食的频率、孩子的睡眠模式、性情；c)父母 影响因素：牙科知识、态度和自我描述的口腔健康、教育 水平，种族认同，日托安排，对试图做出 改变或承担新的责任。这项研究旨在作为试点。 研究以产生进一步的假设。

项目成果

Clinical outcomes for early childhood caries: influence of aggressive dental surgery.

• 发表时间: 2004-05
• 期刊: Journal of dentistry for children
• 影响因子: 0.8
• 作者: C. E. Graves;Robert J. Berkowitz;H. Proskin;I. Chase;P. Weinstein;Ronald J. Billings

Clinical outcomes for Early Childhood Caries (ECC): the influence of salivary mutans streptococci levels.

儿童早期龋齿 (ECC) 的临床结果：唾液变形链球菌水平的影响。

• 发表时间: 2004
• 期刊: European journal of paediatric dentistry
• 影响因子: 3.6
• 作者: Chase,I;Berkowitz,RJ;Mundorff-Shrestha,SA;Proskin,HM;Weinstein,P;Billings,R
• 通讯作者: Billings,R

Clinical outcomes for Early Childhood Caries (ECC): the influence of health locus of control.

儿童早期龋齿 (ECC) 的临床结果：健康控制点的影响。

• 发表时间: 2004
• 期刊: European journal of paediatric dentistry
• 影响因子: 3.6
• 作者: Chase,I;Berkowitz,RJ;Proskin,HM;Weinstein,P;Billings,R
• 通讯作者: Billings,R