PRESCHOOL MOTOR & FUNCTIONAL PERFORMANCE OF TWO COHORTS

随着低出生体重儿存活率的提高， 学期前跟踪研究的重点已经转移到更好地了解 关于围产期发病率的范围和性质。这个项目的目的是 探讨早产儿与学龄前儿童运动障碍的关系 按相似围产期风险分类的两个队列的功能表现 出生时间相差十岁。运动能力在四个特定领域进行评估： 一般运动、粗大运动、精细运动和视觉运动的整合。 功能性能评估执行以下任务的一致能力 日常生活和预期的社会角色。背景是主要的区域 为高危婴儿提供护理，并在以下情况下获得最高评级 在存活率、住院时间和结局质量方面与其他患者相比。数据用于 作为188人研究的一部分，收集了出生于1985至89年间的第一批人 对足月儿和早产儿从出生到出生的纵向研究 8岁。这一样本显示4岁时运动功能显著延迟， 与8岁时表现不佳的维度有关。 应用程序需要资源来招聘和执行完整的运动和 出生于4岁的后一个队列2的功能表现评估 1996年至1997年，并按围产期风险进行了相同的分层。鉴于增加的 2号队列的脆弱、较低的出生体重和较年轻的孕周， 假设运动和功能表现会下降 在几十年之间。有两个具体目标。目标1调查以下因素的影响 两个NICU样本对运动和功能表现的围产期风险 幸存者分为：1)健康足月组；2)早产/有内科疾病 3)早产/神经疾病组。目标2比较了马达和 两个分层样本的功能性能。此应用程序是 独一无二的是，它提供了提供关于 新的新生儿进展导致的运动后遗症，以及复制 在前一个队列的孩子中发现了潜在的有害结果。 队列比较结果对于全面理解这一范围至关重要 在先进的新生儿技术的时间范围内，早产运动后遗症的风险。

With increased survival rates for low birth weight infants, the focus of pre-term follow-up studies has shifted to gain a better understanding of the scope and nature of perinatal morbidity. The purpose of this project is to investigate the relationship between prematurity and preschool motor and functional performance in two cohorts categorized by similar perinatal risk and born ten years apart. Motor ability is evaluated in four specific areas: general motor, gross motor, fine motor, and visual motor integration. Functional performance evaluates the consistent ability to perform the tasks of daily living and expected social roles. The setting is the major regional source of care for high-risk infants and has achieved the highest ratings when compared to others in survival, length of stay and quality of outcome. Data for Cohort 1, born between 1985 to 89, were collected as part of a study of 188 full term and pre-term children who were studied longitudinally from birth to age 8. This sample showed substantial delays in motor function at age 4, which are associated with dimensions of poor school performance at age 8. This application requests resources to recruit and conduct complete motor and functional performance assessment of a later cohort at age 4, Cohort 2, born in 1996 to 97 and identically stratified by perinatal risk. Given the increased fragility, lower birthweight and younger gestational ages of Cohort 2, it is hypothesized that there will be a decline in motor and functional performance between decades. There are two specific aims. Aim 1 investigates the effects of perinatal risk on motor and functional performance in two samples of NICU survivors stratified as: 1) healthy full term group; 2) pre-term/medically ill group; and 3) pre-term/neurologically ill group. Aim 2 compares the motor and functional performance of the two stratified samples. This application is unique in that it affords the opportunity to provide critical information about motor sequelae resulting from new neonatal advances, as well as replicate potentially deleterious outcomes found in the children of the earlier cohort. Cohort comparison results are crucial in terms of understanding the full range of pre-term motor sequelae within a time frame of advanced neonatal technology.