PRESCHOOL MOTOR & FUNCTIONAL PERFORMANCE OF TWO COHORTS

随着低出生体重儿存活率的提高， 足月前随访研究的重点已转向更好地了解 围产期发病的范围和性质。该项目的目的是 调查早产和学龄前运动之间的关系 按相似围产期风险分类的两个队列的功能表现 出生相差十年。运动能力在四个特定领域进行评估： 普通运动、粗大运动、精细运动和视觉运动整合。 功能绩效评估执行任务的一致能力 日常生活和预期的社会角色。环境是主要区域 高危婴儿的护理来源，并在以下情况下获得了最高评级： 在生存率、住院时间和结果质量方面与其他人相比。数据为 第 1 组出生于 1985 年至 89 岁之间，是一项针对 188 名儿童的研究的一部分 对足月儿和早产儿进行纵向研究，从出生到 8 岁时。该样本在 4 岁时表现出运动功能显着延迟，这 与 8 岁时学校表现不佳的维度有关。这 应用程序请求资源来招募和进行完整的运动和 对 4 岁时出生的后来队列（队列 2）进行功能表现评估 1996 年至 97 年，按围产期风险进行相同分层。鉴于增加的 第 2 组的脆弱性、出生体重较低和胎龄较小， 假设运动和功能表现会下降 几十年之间。有两个具体目标。目标 1 研究以下因素的影响 NICU 两个样本中运动和功能表现的围产期风险 幸存者分层为：1）健康足月组； 2) 早产/患病 团体； 3) 早产儿/神经系统疾病组。目标 2 比较电机和 两个分层样本的功能性能。这个应用程序是 其独特之处在于它提供了提供有关以下方面的关键信息的机会： 新生儿新进展导致的运动后遗症，以及复制 在早期队列的孩子中发现了潜在的有害结果。 队列比较结果对于理解整个范围至关重要 在先进的新生儿技术的时间内解决早产运动后遗症的问题。

With increased survival rates for low birth weight infants, the focus of pre-term follow-up studies has shifted to gain a better understanding of the scope and nature of perinatal morbidity. The purpose of this project is to investigate the relationship between prematurity and preschool motor and functional performance in two cohorts categorized by similar perinatal risk and born ten years apart. Motor ability is evaluated in four specific areas: general motor, gross motor, fine motor, and visual motor integration. Functional performance evaluates the consistent ability to perform the tasks of daily living and expected social roles. The setting is the major regional source of care for high-risk infants and has achieved the highest ratings when compared to others in survival, length of stay and quality of outcome. Data for Cohort 1, born between 1985 to 89, were collected as part of a study of 188 full term and pre-term children who were studied longitudinally from birth to age 8. This sample showed substantial delays in motor function at age 4, which are associated with dimensions of poor school performance at age 8. This application requests resources to recruit and conduct complete motor and functional performance assessment of a later cohort at age 4, Cohort 2, born in 1996 to 97 and identically stratified by perinatal risk. Given the increased fragility, lower birthweight and younger gestational ages of Cohort 2, it is hypothesized that there will be a decline in motor and functional performance between decades. There are two specific aims. Aim 1 investigates the effects of perinatal risk on motor and functional performance in two samples of NICU survivors stratified as: 1) healthy full term group; 2) pre-term/medically ill group; and 3) pre-term/neurologically ill group. Aim 2 compares the motor and functional performance of the two stratified samples. This application is unique in that it affords the opportunity to provide critical information about motor sequelae resulting from new neonatal advances, as well as replicate potentially deleterious outcomes found in the children of the earlier cohort. Cohort comparison results are crucial in terms of understanding the full range of pre-term motor sequelae within a time frame of advanced neonatal technology.