PRESCHOOL MOTOR & FUNCTIONAL PERFORMANCE OF TWO COHORTS
PRESCHOOL MOTOR & FUNCTIONAL PERFORMANCE OF TWO COHORTS
批准号:
6042767
负责人:
Mary C Sullivan
金额:
$7.74万
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-04-01 至 2002-03-31
关键词:
behavioral /social science research tag clinical research congenital nervous system disorder functional ability human subject infant mortality longitudinal human study low birth weight infant human neonatal intensive care perinatal premature infant human preschool child (1-5) psychomotor function pulmonary surfactants
中文摘要
随着低出生体重婴儿存活率的提高,
早产儿随访研究的重点已经转移到更好地了解
围产期发病率的范围和性质。本项目的目的是
探讨早产与学龄前运动的关系,
按相似的围产期风险分类的两个队列的功能表现,
出生相隔十年。运动能力在四个特定领域进行评估:
一般运动、粗大运动、精细运动和视觉运动整合。
功能性能评估执行以下任务的持续能力:
日常生活和预期的社会角色。背景是主要的区域
高风险婴儿的护理来源,并取得了最高评级,
在生存期、住院时间和结局质量方面与其他患者相比。数据
队列1,出生于1985年至89年,作为188名研究的一部分,
对足月和早产儿从出生到
八岁。这个样本在4岁时表现出运动功能的实质性延迟,
与8岁时学校表现不佳的维度有关。这
申请要求资源,以招聘和进行完整的电机和
在4岁时对随后队列(队列2,出生于
1996年至97年,并按围产期风险进行相同分层。鉴于增加
脆弱性、出生体重较低和胎龄较低,
假设运动和功能表现会下降,
几十年之间。有两个具体目标。目标1研究了
新生儿重症监护室两例患者围产期运动和功能风险
存活者分层为:1)健康足月组; 2)早产/医学疾病
早产儿/神经系统疾病组。目标2比较了电机和
两个分层样本的功能表现。本申请是
独特之处在于它提供了提供关键信息的机会,
新生儿进展导致的运动后遗症,以及重复
在早期队列的儿童中发现的潜在有害结果。
队列比较结果对于了解整个范围至关重要
在先进的新生儿技术的时间框架内早产运动后遗症。
英文摘要
With increased survival rates for low birth weight infants, the
focus of pre-term follow-up studies has shifted to gain a better understanding
of the scope and nature of perinatal morbidity. The purpose of this project is
to investigate the relationship between prematurity and preschool motor and
functional performance in two cohorts categorized by similar perinatal risk and
born ten years apart. Motor ability is evaluated in four specific areas:
general motor, gross motor, fine motor, and visual motor integration.
Functional performance evaluates the consistent ability to perform the tasks of
daily living and expected social roles. The setting is the major regional
source of care for high-risk infants and has achieved the highest ratings when
compared to others in survival, length of stay and quality of outcome. Data for
Cohort 1, born between 1985 to 89, were collected as part of a study of 188
full term and pre-term children who were studied longitudinally from birth to
age 8. This sample showed substantial delays in motor function at age 4, which
are associated with dimensions of poor school performance at age 8. This
application requests resources to recruit and conduct complete motor and
functional performance assessment of a later cohort at age 4, Cohort 2, born in
1996 to 97 and identically stratified by perinatal risk. Given the increased
fragility, lower birthweight and younger gestational ages of Cohort 2, it is
hypothesized that there will be a decline in motor and functional performance
between decades. There are two specific aims. Aim 1 investigates the effects of
perinatal risk on motor and functional performance in two samples of NICU
survivors stratified as: 1) healthy full term group; 2) pre-term/medically ill
group; and 3) pre-term/neurologically ill group. Aim 2 compares the motor and
functional performance of the two stratified samples. This application is
unique in that it affords the opportunity to provide critical information about
motor sequelae resulting from new neonatal advances, as well as replicate
potentially deleterious outcomes found in the children of the earlier cohort.
Cohort comparison results are crucial in terms of understanding the full range
of pre-term motor sequelae within a time frame of advanced neonatal technology.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Allostatic Load & Epigenetic Mechanisms in Lifecourse Trajectories of Premature Infants at Age 30
-
批准号:9888435
-
项目类别:
-
资助金额:$62.35万
-
财政年份:2019
-
负责人:Mary C Sullivan
-
依托单位:
Allostatic Load & Epigenetic Mechanisms in Lifecourse Trajectories of Premature Infants at Age 30
-
批准号:10094005
-
项目类别:
-
资助金额:$60.04万
-
财政年份:2019
-
负责人:Mary C Sullivan
-
依托单位:
Risk & Protection in Trajectories of Preterm Infants: Birth to Adulthood
-
批准号:7848806
-
项目类别:
-
资助金额:$2.49万
-
财政年份:2009
-
负责人:Mary C Sullivan
-
依托单位:
BRAIN STRUCTURE AND ACTIVATION IN CHILDREN BORN PRETERM
-
批准号:6973540
-
项目类别:
-
资助金额:$2.23万
-
财政年份:2004
-
负责人:Mary C Sullivan
-
依托单位:
PRESCHOOL MOTOR & FUNCTIONAL PERFORMANCE OF TWO COHORTS
-
批准号:6388095
-
项目类别:
-
资助金额:$7.98万
-
财政年份:2000
-
负责人:Mary C Sullivan
-
依托单位:
Risk & Protection in Trajectories of Preterm Infants: Birth to Adulthood
-
批准号:8098684
-
项目类别:
-
资助金额:$45.48万
-
财政年份:1994
-
负责人:Mary C Sullivan
-
依托单位:
Longitudinal Trajectories of Adolescents Born Preterm
-
批准号:7212258
-
项目类别:
-
资助金额:$27.77万
-
财政年份:1994
-
负责人:Mary C Sullivan
-
依托单位:
Risk & Protection in Trajectories of Preterm Infants: Birth to Adulthood
-
批准号:7695009
-
项目类别:
-
资助金额:$13.75万
-
财政年份:1994
-
负责人:Mary C Sullivan
-
依托单位:
Longitudinal Trajectories of Adolescents Born Preterm
-
批准号:6877156
-
项目类别:
-
资助金额:$29.99万
-
财政年份:1994
-
负责人:Mary C Sullivan
-
依托单位:
Risk & Protection in Trajectories of Preterm Infants: Birth to Adulthood
-
批准号:8298190
-
项目类别:
-
资助金额:$44.53万
-
财政年份:1994
-
负责人:Mary C Sullivan
-
依托单位:
Longitudinal Trajectories of Adolescents Born Preterm
-
批准号:7050227
-
项目类别:
-
资助金额:$29.49万
-
财政年份:1994
-
负责人:Mary C Sullivan
-
依托单位:
Risk & Protection in Trajectories of Preterm Infants: Birth to Adulthood
-
批准号:7920936
-
项目类别:
-
资助金额:$46.67万
-
财政年份:1994
-
负责人:Mary C Sullivan
-
依托单位:
Longitudinal Trajectories of Adolescents Born Preterm
-
批准号:6766884
-
项目类别:
-
资助金额:$29.78万
-
财政年份:1994
-
负责人:Mary C Sullivan
-
依托单位:
Risk & Protection in Trajectories of Preterm Infants: Birth to Adulthood
-
批准号:7579601
-
项目类别:
-
资助金额:$53.42万
-
财政年份:1994
-
负责人:Mary C Sullivan
-
依托单位:
海外基金