TRAINING GRANT IN MOLECULAR BIOPHYSICS

分子生物物理学培训补助金

• 批准号: 6150871
• 负责人: Wilma K Olson
• 金额: $ 14.84万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-07-01 至 2004-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6150871
• 关键词: TRAINING; GRANT; MOLECULAR; BIOPHYSICS

Funding is requested for continued support of an interdisciplinary training program in molecular biophysics at Rutgers University. The program offers broad exposure to the experimental and theoretical techniques needed to solve problems in molecular biophysics together with in-depth training with a specific research problem. The graduate faculty of Rutgers University includes one of the largest and most active groups of molecular biophysicists in the country with interests ranging from molecular and submolecular problems to aspects of cellular organization and intact organisms. The training faculty are spread over four graduate programs at Rutgers and seven departments at Rutgers and the adjacent Robert Wood Johnson Medical School (formerly Rutgers Medical School) of the University of Medicine and Dentistry of New Jersey. There are significant research programs in X-ray crystallography and diffraction (Edward Arnold, Helen M. Berman, Barbara M. Brodsky, Millie M. Georgiadis, Ann Stock), nuclear magnetic resonance (Jean S. Baum, Gaetano T. Montelione), theoretical methods (Karsten Krogh- Jesperson, Ronald M. Levy, Gerald S. Manning, Wilma K. Olson), artificial intelligence (Casimir A. Kulikowski, Martin Farach), continuum mechanics (Bernard D. Coleman), biothermodynamics and spectroscopy (Kenneth J. Breslauer, Jeehiun K. Lee. Richard Ludescher, Tariq M. Rana, T.J. Thomas), electron microscopy (Donald A. Winkelmann), and biochemical synthesis and design (Stephen Anderson, Richard H. Ebright, Marc R. Gartenberg, Sarah E. Hitchcock-Dregregori, Masayori Inouye, Stephen S. Isied, Roger A. Jones, John W. Taylor). The faculty are a closely knit group with common interests in macromolecular structure, function, and interactions and with a history of fruitful interactions. Prospective trainees enter with undergraduate degrees in biology, chemistry, computer science, engineering, mathematics and physics. The program entails formal graduate courses, laboratory rotations, seminars, and dissertation research. Research groups are well equipped and well supported from extramural sources. The senior faculty have extensive experience in training students and the junior faculty are among the most promising young scientists in the nation. The intellectual climate is excellent and conducive to nurturing future research opportunities. Rutgers University and the University of Medicine of Dentistry have outstanding computational, imaging, NMR, and X-ray facilities available for training in molecular biophysics. The universities, together with the New Jersey Commission on Science and Technology, also jointly sponsor the New Jersey Center for Advanced Biotechnology and Medicine which has a strong research focus in molecular biophysics. The training program not only helps to meet national needs for personnel trained to apply the tools and concepts of the physical sciences to the solution of significant biological problems but also helps to enhance the academic environment within Rutgers University. The requested funds help to attract a pool of outstanding predoctoral students, to unify existing graduate offerings, and to offer an independent graduate curriculum in molecular biophysics.

请求资金继续支持罗格斯大学分子生物物理学跨学科培训项目。该计划提供解决分子生物物理学问题所需的实验和理论技术的广泛接触，以及针对特定研究问题的深入培训。罗格斯大学的研究生院包括美国最大、最活跃的分子生物物理学家团体之一，其兴趣范围从分子和亚分子问题到细胞组织和完整生物体的各个方面。培训教师分布在罗格斯大学的四个研究生项目、罗格斯大学的七个系以及邻近的新泽西医学和牙科大学罗伯特伍德约翰逊医学院（前罗格斯医学院）。在X射线晶体学和衍射（Edward Arnold、Helen M. Berman、Barbara M. Brodsky、Millie M. Georgiadis、Ann Stock）、核磁共振（Jean S. Baum、Gaetano T. Montelione）、理论方法（Karsten Krogh- Jesperson、Ronald M. Levy、Gerald S. Manning、Wilma K. Olson）等方面有重要的研究项目， 人工智能（Casimir A. Kulikowski、Martin Farach）、连续介质力学（Bernard D. Coleman）、生物热力学和光谱学（Kenneth J. Breslauer、Jeehiun K. Lee. Richard Ludescher、Tariq M. Rana、T.J. Thomas）、电子显微镜（Donald A. Winkelmann）和生化合成 和设计（Stephen Anderson、Richard H. Ebright、Marc R. Gartenberg、Sarah E. Hitchcock-Dregregori、Masayori Inouye、Stephen S. Isied、Roger A. Jones、John W. Taylor）。教师们是一个紧密结合的群体，对大分子结构、功能和相互作用有着共同的兴趣，并且有着富有成效的相互作用的历史。未来的学员将获得生物学、化学、计算机科学、工程学、数学和物理学的本科学位。该项目包括正式的研究生课程、实验室轮转、研讨会和论文研究。研究小组装备精良，并得到外部资源的大力支持。高级教师在培养学生方面拥有丰富的经验，初级教师是全国最有前途的年轻科学家之一。学术氛围极佳，有利于培育未来的研究机会。罗格斯大学和牙科医学大学拥有出色的计算、成像、核磁共振和 X 射线设施，可用于分子生物物理学的培训。这些大学还与新泽西州科学技术委员会共同主办了新泽西州先进生物技术和医学中心，该中心的研究重点是分子生物物理学。该培训计划不仅有助于满足国家对受训人员应用物理科学工具和概念解决重大生物学问题的需求，而且有助于改善罗格斯大学内部的学术环境。所申请的资金有助于吸引一批优秀的博士前学生，统一现有的研究生课程，并提供独立的分子生物物理学研究生课程。