Molecular Biophysics Training Grant

分子生物物理学培训补助金

• 批准号: 10628259
• 负责人: Tanja Kortemme
• 金额: $ 40.63万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10628259
• 关键词: Biophysics; Grant; Molecular; Training

PROJECT SUMMARY / ABSTRACT The mission of the UCSF Graduate Program in Biophysics is to train diverse students to tackle some of the most challenging problems in biology and biomedicine at the interfaces with physics, mathematics, chemistry, and engineering, while equipping our graduates with the knowledge, tools, and skills to become leaders in academic science, biotechnology, and affiliated sectors. With the extraordinarily rapid advances in technologies and the new biological data they generate, there is an increasing need to understand the molecular basis for complex biological behavior. Concurrently, advances in the ability to computationally model molecular behavior are transforming biomedical research. To train leaders who can address the most critical questions in their fields through integration of these disciplines, our program is designed to (i) provide our students with both a foundation in quantitative, physical approaches and a sophisticated understanding of biology; (ii) bridge computational and experimental biophysical methods; (iii) create an environment where all students, including those from historically excluded groups, disadvantaged backgrounds, and persons with a disability, are supported and succeed; and (iv) promote key skills for success in a wide range of careers. From the start, “Onboarding” and community circles emphasize our values of collaboration, a supportive community, and ethically responsible rigorous research. Our well-tested and new project- and team-based based core courses lay the foundation to conceptualize, design, and execute innovative thesis projects. These courses also build a foundation in the communication, leadership, management, and team skills we emphasize throughout the graduate training. Current and new “minicourses” and “State of the Field” discussions facilitate deep exploration of research topics in small groups with faculty experts, allow the curriculum to stay current with latest scientific developments, and allow the students to identify important research questions. Students can participate in career preparation workshops and internships, and many take on leadership roles in outreach and teaching. Our alumni include leaders in both academia and industry, including several who have started successful companies, and they actively participate in career development through our Biophysics Alumni Speaker Forum and the new Biophysics Alumni Mentorship Program. Our goal to enhance diversity at all levels requires activities to ensure continued success, formalized through an actionable plan that includes required faculty training on mentorship across differences and increased guidance and support of trainees throughout the PhD, in addition to the Biophysics Outreach Initiative and improved admissions processes. The 54 Biophysics faculty participating in this training program have an outstanding record of interdisciplinary and collaborative research, and a strong commitment to mentorship and training. Chosen from a highly qualified pool of diverse Biophysics applicants from a range of quantitative disciplines, we plan to appoint 6 trainees for a duration of 2 years (in their 1st and 2nd year), for a total of 12 annual slots on this training grant.

项目摘要/摘要 UCSF生物物理学研究生课程的使命是培养不同的学生来解决一些问题。 生物学和生物医学中最具挑战性的问题，与物理，数学，化学， 和工程，同时装备我们的毕业生的知识，工具和技能，成为领导者， 学术科学、生物技术和附属部门。随着科学的飞速发展， 技术及其产生的新生物数据，越来越需要了解 复杂生物行为的分子基础。与此同时，计算机建模能力的进步 分子行为正在改变生物医学研究。培养能够解决最关键问题的领导者 通过这些学科的整合，在他们的领域的问题，我们的计划旨在（i）提供我们的 学生既有定量的基础，物理方法和复杂的理解 生物学;（ii）连接计算和实验生物物理方法;（iii）创造一个所有人都能参与的环境 学生，包括那些从历史上被排斥的群体，弱势背景，和人， 残疾人，得到支持和成功;（iv）促进在广泛的职业生涯中取得成功的关键技能。从 一开始，“入职”和社区圈强调我们的合作价值观，一个支持性的社区， 和道德上负责任的严谨研究。我们经过充分测试的新项目和基于团队的核心 课程奠定了概念化，设计和执行创新论文项目的基础。这些课程 同时也为我们所强调的沟通、领导、管理和团队技能打下基础 在毕业生培训中。当前和新的“小型课程”和“实地状况”讨论有助于 与教师专家小组深入探索研究课题，使课程保持最新 与最新的科学发展，并允许学生确定重要的研究问题。学生 可以参加职业准备研讨会和实习，许多人在以下方面担任领导角色： 推广和教学。我们的校友包括学术界和工业界的领导者，其中包括几位拥有 创办了成功的公司，并通过我们的生物物理学积极参与职业发展 校友演讲论坛和新的生物物理学校友导师计划。我们的目标是提高多样性， 所有级别都需要通过一个可操作的计划正式化的活动，以确保持续的成功，该计划包括 需要对教师进行跨差异指导培训，并增加对学员的指导和支持 在整个博士学位，除了生物物理学外展计划和改进的录取过程。的 54生物物理学教师参加这个培训计划有一个跨学科的杰出记录， 合作研究，以及对指导和培训的坚定承诺。从一个高素质的 来自一系列定量学科的多样化生物物理学申请者，我们计划任命6名学员， 为期2年（第一年和第二年），每年共有12个培训补助金名额。