ENERGY CONSERVATION AND CANCER TREATMENT RELATED FATIGUE

尽管癌症治疗相关疲劳(CRF)被认为是 癌症治疗最常见的副作用，科学的 其管理的基础极其有限。这是随机的 对照临床试验测试基于电话的能量 保护/活动管理(ECAM)干预 它对感知疲劳程度和选定领域的影响 生活质量(功能水平和消极情绪)。一个 次要目的是检查另一方的关系 对慢性肾功能衰竭的影响和症状。这项研究是由共同的 疾病的感觉模型。开始治疗肺部疾病的患者， 乳腺癌和结直肠癌将被随机分配到ECAM 干预组或注意对照组。ECAM包括 信息、应对技能培训和评价组成部分 符合常识模型以及 先前的研究测试心理教育干预与 癌症患者。ECAM小组的参与者将收到 由特派提供的三次电话咨询会议 受训的肿瘤科护士。干预的时机与 每种治疗类型的疲劳开始。个人 接受化疗(CTX)的患者在几周内接受干预 1、2和3个治疗周期，同时进行放射治疗 治疗(RT)在第3、4、5周接受干预 治疗。主要的结果--疲劳感， 功能受限和消极情绪-将被测量 所有参与者在第一次治疗(基线)之前。那些 48小时后接受CTX完整的随访措施 第二周期和第三周期治疗前48小时， 预计高疲劳和低疲劳时间。接受RT的人 在治疗的第六周内完成随访措施 治疗结束后1个月，高峰期 和低疲劳度。数据将使用多变量进行分析 重复测量协方差分析。这项研究的发现 研究将有助于肿瘤学的科学基础 慢性肾衰治疗的护理实践。

Although cancer treatment-related fatigue (CRF) is recognized as the most common side effect of cancer treatment, the scientific basis for its management is extremely limited. This randomized controlled clinical trial tests a telephone based energy conservation/activity management (ECAM) intervention with regard to its effects o perceived level of fatigue and selected domains of quality of life (level of functioning and negative mood). A secondary aim is to examine the relationship of other side effects and symptoms to CRF. The study is guided by the Common Sense Model of illness. Patients beginning treatment for lung, breast, and colorectal cancer will be randomized to an ECAM intervention or attentional control group. The ECAM includes information, coping skills training, and evaluation components that are consistent with the Common Sense Model as well as previous research testing psychoeducational interventions with cancer patients. Participants in the ECAM group will receive three telephone counseling sessions delivered by specially trained oncology nurses. Timing of the intervention is tied to the onset of fatigue for each type of treatment. Individuals having chemotherapy (CTX) receive the intervention during weeks 1, 2, and 3 of the treatment cycle while those having radiation therapy (RT) receive the intervention during weeks 3, 4, and 5 of treatment. The primary outcomes - perception of fatigue, limitation of functioning, and negative mood - will be measured prior to first treatment (baseline) for all participants. Those receiving CTX complete follow-up measures 48 hours after the second cycle and 48 hours before the third cycle of treatment, expected times of high and low fatigue. Those receiving RT complete follow-up measures during the sixth week of treatment and one month after the completion of treatment, times of high and low fatigue. Data will be analyzed using multivariate repeated measures analysis of covariance. The findings of this study will contribute to the scientific basis for oncology nursing practice for CRF management.