ENERGY CONSERVATION AND CANCER TREATMENT RELATED FATIGUE

尽管癌症治疗相关疲劳（CRF）被认为是 癌症治疗最常见的副作用，科学 其管理基础极为有限。 这项随机 对照临床试验测试了一种基于电话的能量 保护/活动管理（ECAM） 对疲劳程度和选定领域的影响 生活质量（功能水平和消极情绪）。 一 第二个目的是检查对方的关系 CRF的作用和症状。 这项研究是由共同指导的 疾病的感觉模型。 开始肺部治疗的患者， 乳腺癌和结直肠癌将随机分配至ECAM组 干预组或注意力控制组。 ECAM包括 信息、应对技能培训和评估组成部分 符合常识模型，以及 以前的研究测试心理教育干预与 癌症患者。 ECAM组的参与者将获得 三次电话辅导， 训练有素的肿瘤科护士 干预的时机与 每种治疗类型的疲劳发作。 个人 接受化疗（CTX）的患者在周内接受干预 治疗周期的第1、2和3天， 治疗（RT）在第3、4和5周期间接受干预。 治疗 主要结果-疲劳感， 功能限制和消极情绪-将被测量 所有受试者的首次治疗前（基线）。 那些 接受CTX后48小时完成随访措施 第二个周期和第三个周期治疗前48小时， 高疲劳和低疲劳的预期时间。 接受RT的人 在治疗第6周期间完成随访措施 治疗完成后一个月， 低疲劳。 将使用多变量分析数据 重复测量协方差分析。 这项研究的结果 这项研究将有助于肿瘤学的科学基础 CRF管理的护理实践。

Although cancer treatment-related fatigue (CRF) is recognized as the most common side effect of cancer treatment, the scientific basis for its management is extremely limited. This randomized controlled clinical trial tests a telephone based energy conservation/activity management (ECAM) intervention with regard to its effects o perceived level of fatigue and selected domains of quality of life (level of functioning and negative mood). A secondary aim is to examine the relationship of other side effects and symptoms to CRF. The study is guided by the Common Sense Model of illness. Patients beginning treatment for lung, breast, and colorectal cancer will be randomized to an ECAM intervention or attentional control group. The ECAM includes information, coping skills training, and evaluation components that are consistent with the Common Sense Model as well as previous research testing psychoeducational interventions with cancer patients. Participants in the ECAM group will receive three telephone counseling sessions delivered by specially trained oncology nurses. Timing of the intervention is tied to the onset of fatigue for each type of treatment. Individuals having chemotherapy (CTX) receive the intervention during weeks 1, 2, and 3 of the treatment cycle while those having radiation therapy (RT) receive the intervention during weeks 3, 4, and 5 of treatment. The primary outcomes - perception of fatigue, limitation of functioning, and negative mood - will be measured prior to first treatment (baseline) for all participants. Those receiving CTX complete follow-up measures 48 hours after the second cycle and 48 hours before the third cycle of treatment, expected times of high and low fatigue. Those receiving RT complete follow-up measures during the sixth week of treatment and one month after the completion of treatment, times of high and low fatigue. Data will be analyzed using multivariate repeated measures analysis of covariance. The findings of this study will contribute to the scientific basis for oncology nursing practice for CRF management.