ENERGY CONSERVATION AND CANCER TREATMENT RELATED FATIGUE

尽管癌症治疗相关疲劳（CRF）被认为是 癌症治疗最常见的副作用，科学依据 其管理基础极其有限。 这个随机 受控临床试验测试基于电话的能量 保护/活动管理（ECAM）干预 其对疲劳感知程度和选定领域的影响 生活质量（功能水平和消极情绪）。 一个 次要目的是考察对方的关系 对 CRF 的影响和症状。 该研究以共同 疾病的感知模型。 开始肺部治疗的患者， 乳腺癌和结直肠癌将被随机分配至 ECAM 干预组或注意力对照组。 ECAM 包括 信息、应对技能培训和评估部分 符合常识模型以及 先前的研究测试了心理教育干预措施 癌症患者。 ECAM小组的参与者将获得 专门提供的三场电话咨询 受过培训的肿瘤科护士。 干预的时间与 每种治疗类型的疲劳发生情况。 个人 化疗（CTX）在数周内接受干预 接受放射治疗的患者在治疗周期的第 1、2 和 3 个周期中 治疗 (RT) 在治疗的第 3、4 和 5 周内接受干预 治疗。 主要结果 - 疲劳感， 功能限制和负面情绪 - 将被测量 所有参与者在第一次治疗（基线）之前。 那些 收到CTX后48小时完成后续措施 第二个周期和第三个周期治疗前48小时， 预期的高疲劳和低疲劳时间。 接受 RT 的人 治疗第六周期间完成后续措施 治疗完成后一个月，高倍数 和低疲劳度。 将使用多变量分析数据 协方差的重复测量分析。 本次调查结果 研究将为肿瘤学奠定科学基础 CRF 管理的护理实践。

Although cancer treatment-related fatigue (CRF) is recognized as the most common side effect of cancer treatment, the scientific basis for its management is extremely limited. This randomized controlled clinical trial tests a telephone based energy conservation/activity management (ECAM) intervention with regard to its effects o perceived level of fatigue and selected domains of quality of life (level of functioning and negative mood). A secondary aim is to examine the relationship of other side effects and symptoms to CRF. The study is guided by the Common Sense Model of illness. Patients beginning treatment for lung, breast, and colorectal cancer will be randomized to an ECAM intervention or attentional control group. The ECAM includes information, coping skills training, and evaluation components that are consistent with the Common Sense Model as well as previous research testing psychoeducational interventions with cancer patients. Participants in the ECAM group will receive three telephone counseling sessions delivered by specially trained oncology nurses. Timing of the intervention is tied to the onset of fatigue for each type of treatment. Individuals having chemotherapy (CTX) receive the intervention during weeks 1, 2, and 3 of the treatment cycle while those having radiation therapy (RT) receive the intervention during weeks 3, 4, and 5 of treatment. The primary outcomes - perception of fatigue, limitation of functioning, and negative mood - will be measured prior to first treatment (baseline) for all participants. Those receiving CTX complete follow-up measures 48 hours after the second cycle and 48 hours before the third cycle of treatment, expected times of high and low fatigue. Those receiving RT complete follow-up measures during the sixth week of treatment and one month after the completion of treatment, times of high and low fatigue. Data will be analyzed using multivariate repeated measures analysis of covariance. The findings of this study will contribute to the scientific basis for oncology nursing practice for CRF management.