课题基金 / 基金详情

NURSING INTERVENTION TO IMPROVE ANTIVIRAL ADHERENCE

NURSING INTERVENTION TO IMPROVE ANTIVIRAL ADHERENCE
提高抗病毒治疗依从性的护理干预
批准号:
6186884
负责人:
Ann Bartley Williams
金额:
$54.21万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-09-30 至 2002-08-31

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中文摘要
翻译
描述(改编自摘要):主要研究者 计划进行一项前瞻性随机临床试验, 感染者(N=2000),以测试基于家庭的 基于保乐成人教育原则的护理干预 旨在提高对高效抗逆转录病毒药物的依从性 HAART(HAART)。将以蜂蜜为基础的护理干预与 在流动护理环境中提供的标准护理。粘附 将使用药物事件监测系统测量结局 (MEMS)数据,自我报告和未公布的药丸计数。实验 参与者将每周接受一次家庭干预, 每周,每隔一周十二周,每月一次,一年 然后其他具体目标是:(1)描述关系 家庭护理干预和生物措施之间的关系, 临床结局(血浆定量HIV RNA水平和CD 4淋巴细胞 (2)描述家庭护理与社区卫生服务的关系 干预和临床结果的主观测量(参与者的 (3)健康感知;(4)健康感知与健康感知之间的关系 家庭护理干预及相关背景因素 依从性(社会支持、对提供者的信任和对目的的了解 HAART)。数据收集方法包括面对面访谈, 微电脑监测技术,未公布的药丸计数,以及医疗 记录基线至干预后6个月的抽象(月 18)。
英文摘要
DESCRIPTION (adapted from the Abstract): The Principal Investigator proposes to conduct a prospective randomized clinical trial of HIV- infected individuals (N=2000) to test the effectiveness of a home-based nursing intervention based on the adult education principles of Paole Freire and designed to improve adherence to highly active anti-retroviral therapies (HAART). The hone-based nursing intervention will be compared to standard nursing care provided in a ambulatory care setting. The adherence outcome will be measured using the medication event monitoring system (MEMS) data, self-report, and unannounced pill counts. Experimental participants will receive the home-based intervention weekly for twelve weeks, every other week for twelve weeks, and monthly for one year thereafter. Other specific aims are to: (1) describe the relationship between the home-based nursing intervention and biologic measures of clinical outcome (plasma quantitative HIV RNA levels and CD4 lymphocyte counts); (2) describe the relationship between the home-based nursing intervention and a subjective measure of clinical outcome (participant's perception of health stratus); and (3) explore the relationship between the home-based nursing intervention and contextual factors related to adherence (social support, trust in provider, and knowledge of the purpose of HAART). Data collections methods include face-to-face interviews, microcomputer monitoring technology, unannounced pill counts, and medical record abstraction at baseline through 6 months post intervention (Month 18).
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Xiangya-UCLA HIV/AIDS Nursing Research Initiative
Developing an ART Adherence Intervention in South Central China
  • 批准号:
    7756339
  • 项目类别:
  • 资助金额:
    $28.02万
  • 财政年份:
    2009
  • 负责人:
    Ann Bartley Williams
  • 依托单位:
Developing an ART Adherence Intervention in South Central China
Developing an ART Adherence Intervention in South Central China
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