NEUROBIOLOGICAL ASPECTS OF AGING

该指导临床科学家发展计划的目的是支持与衰老相关的神经科学学科中优秀医生学员的职业发展，从而实现研究独立性。培训将作为一个联合项目进行，利用当地神经科学界的多样化和广泛的资源，包括加州大学圣地亚哥分校，斯克里普斯研究基金会，索尔克研究所和伯纳姆基金会。该计划的优秀申请人将在UCSD神经科学系的临床神经病学计划的本地和毕业居民以及全国神经病学培训计划中招募。每年申请2个职位，为期5年，共计培训职位。该计划将由神经科学系管理，这是一个联合基础科学临床部门。该学院在神经系统和衰老研究的遗传，分子，细胞系统，行为和建模方面具有相当的实力。该培训计划将为被任命者提供三种类型的学术经验，以实现研究独立性。1)基础神经科学培训，通过正式的神经科学研究生课程工作和实验室研究轮换完成，2）3-4年的密集指导研究，3）研讨会，老化课程和讲座的连续课程。有博士学位的实习生。学位将有机会参加UCSD神经科学研究生课程，并提前获得神经科学博士学位。该培训计划旨在让学员接触到神经科学主题的气息，这些主题需要从全面和学术Vantage来处理与衰老相关的问题，从基因表达的研究到整个系统/行为方法。然后，个别学员将选择一个学科，在其中重点和促进职业研究课题。

The purpose of this Mentored Clinical Scientist Development Program is to support the career development of outstanding physician trainees in an aging-related neuroscience discipline, leading to research independence. Training will be conducted as a joint program taking advantage of the diverse and extensive resource of the local neuroscience community, including the University of California-San Diego, Scripps Research Foundation, the Salk Institute, and the Burnham Foundation. Outstanding applicants for the program will be recruited both locally and graduating residents of the clinical neurology program in the Department of Neurosciences at UCSD, and from neurology training programs nationally. 2 slots per year are requested for a 5 year period, totaling training positions. The program will be administered by the Department of Neurosciences, a joint basic science clinical department. The faculty possesses considerable strength in the genetic, molecular, cellular systems, behavioral and modeling aspects of nervous system and aging research. The training program will provide appointees three types of academic experiences to lead to research independence. 1) Basic neuroscience training, accomplished by formal Neuroscience Graduate Program course work and laboratory research rotations, 2) a 3-4 year period of intensive mentored research, and 3) a continuous curriculum of symposia, coursework in aging, and lectures. Trainees who do have a Ph.D. degree will have the opportunity to enroll in the UCSD Neuroscience Graduate Program and early a Neuroscience doctoral degree. The training program intends to expose the trainees to a breath of neuroscience topics that are required to approach aging-related questions from a comprehensive and scholarly vantage point, ranging from the study of gene expression to whole systems/behavioral approaches. Individual trainees will then choose a discipline within which to focus and foster a career research topic.