NEUROBIOLOGICAL ASPECTS OF AGING

衰老的神经生物学方面

• 批准号: 6371998
• 负责人: LEON J THAL
• 金额: $ 40.76万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-04-01 至 2005-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6371998
• 关键词: aging; health science research potential; neurobiology; training

The purpose of this Mentored Clinical Scientist Development Program is to support the career development of outstanding physician trainees in an aging-related neuroscience discipline, leading to research independence. Training will be conducted as a joint program taking advantage of the diverse and extensive resource of the local neuroscience community, including the University of California-San Diego, Scripps Research Foundation, the Salk Institute, and the Burnham Foundation. Outstanding applicants for the program will be recruited both locally and graduating residents of the clinical neurology program in the Department of Neurosciences at UCSD, and from neurology training programs nationally. 2 slots per year are requested for a 5 year period, totaling training positions. The program will be administered by the Department of Neurosciences, a joint basic science clinical department. The faculty possesses considerable strength in the genetic, molecular, cellular systems, behavioral and modeling aspects of nervous system and aging research. The training program will provide appointees three types of academic experiences to lead to research independence. 1) Basic neuroscience training, accomplished by formal Neuroscience Graduate Program course work and laboratory research rotations, 2) a 3-4 year period of intensive mentored research, and 3) a continuous curriculum of symposia, coursework in aging, and lectures. Trainees who do have a Ph.D. degree will have the opportunity to enroll in the UCSD Neuroscience Graduate Program and early a Neuroscience doctoral degree. The training program intends to expose the trainees to a breath of neuroscience topics that are required to approach aging-related questions from a comprehensive and scholarly vantage point, ranging from the study of gene expression to whole systems/behavioral approaches. Individual trainees will then choose a discipline within which to focus and foster a career research topic.

这项受过指导的临床科学家发展计划的目的是支持与衰老有关的神经科学学科的杰出医师学员的职业发展，从而实现了研究独立性。培训将作为一项联合计划，利用当地神经科学社区的多样化和广泛的资源，包括加利福尼亚大学迭戈大学，斯克里普斯研究基金会，萨尔克研究所和伯纳姆基金会。该计划的杰出申请人将在UCSD神经科学系的临床神经病学计划的本地和毕业居民以及全国的神经病学培训计划中招募。每年要求有2个插槽，为期5年，总培训职位。该计划将由联合基础科学临床部门神经科学系管理。该教师在神经系统和衰老研究的遗传，分子，细胞系统，行为和建模方面具有相当大的力量。该培训计划将为任命的三种类型的学术经验，以导致研究独立性。 1）基本的神经科学培训，由正式的神经科学研究生课程课程工作和实验室研究轮换完成，2）3 - 4年的深入指导研究，3）持续的专题讨论会，衰老课程和讲座的持续课程。确实拥有博士学位的学员学位将有机会参加UCSD神经科学研究生课程和早期神经科学博士学位。该培训计划旨在使受训者接触到神经科学主题的呼吸，这些主题是从全面和学术上的有利位置处理与衰老有关的问题所需的，从基因表达的研究到整个系统/行为方法。然后，个别受训者将选择一门纪律，以便在其中集中精力并培养职业研究主题。