CORE--CELLULAR AND MOLECULAR IMMUNOBIOLOGY

核心——细胞和分子免疫生物学

• 批准号: 6295931
• 负责人: PAUL H GUMERLOCK
• 金额: $ 6.49万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-01 至 1999-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6295931
• 关键词: animal genetic material tag; animal tissue; apoptosis; biomarker; biomedical facility; biopsy; breast neoplasms; cell mediated cytotoxicity; cytotoxicity; gene expression; human genetic material tag; human therapy evaluation; human tissue; interleukin 2; interleukin 6; neoplasm /cancer genetics; nonHodgkin's lymphoma; polymerase chain reaction; southern blotting; transforming growth factors; tumor suppressor genes

Members of the Cellular and Molecular Immunobiology Core have unique expertise in development of clinically relevant assays for gene expression in human tumor samples including small needle biopsies. This allows correlation of tumor genetic expressions with the initial histologic type and grade and response to therapy on protocols in Projects 1 and 2 for mice and patients.

细胞和分子免疫生物学核心的成员具有独特的 基因临床相关测定法的发展专业知识 人类肿瘤样品中的表达，包括小针头活检。 这 允许将肿瘤遗传表达与初始相关 组织学类型和等级以及对方案方案的治疗的反应 小鼠和患者的项目1和2。