CORE--DEVELOPMENTAL

CFAR发展核心的目的是促进 凯斯西储大学的艾滋病相关研究及其 通过促进基础/临床研究的转化， 实验技术，其应用将促进艾滋病相关 研究，促进与其他中心的案例西方的互动 储备大学校园。发展型核心行政结构 已经建立了分发和监测使用发展 通过各种机制筹集资金，包括（1）调查员发起的 可行性研究，（2）具体应用的要求，（3）新的 技术开发，（4）教师招聘，（5）最先进的核心 开发，（6）CFAR补充应用，以及（7）中心间 协同 通过三年期的发展核心活动， 新成员加入了CFAR，5份手稿已经出版，5 国家研究赠款共计290万美元的直接费用，（包括 1少数民族补助金）已获得资助，两名新教员 一个专注于艾滋病相关研究的人被招募到凯斯西方 保留地大学，ELIspot技术已被凯斯专利 西储大学，并由新的CFAR提供服务 细胞因子核心，三个其他CFAR核心已被增强， 制定了中心间方案倡议。 2006 - 2010年要求每年提供150 000美元的发展核心资金， 用于支持上述发展核心计划。在 2006年，75，000美元将用于招聘教师，其余的 用于支持研究者发起的可行性研究和核心 发展在2006年及以后各年，发展核心资金 将由CFAR领导层酌情分发， 这些资金可能在刺激艾滋病相关的 研究活动。

The purpose of the CFAR Developmental Core is to stimulate the growth of AIDS-related research at Case Western Reserve University and its affiliates by fostering translational basic/clinical research developing experimental technologies whose application will advance AIDS-related research, promoting interactions with other Centers on the Case Western Reserve University campus. A Developmental Core administrative structure has been established to distribute and monitor the use of developmental funds through a variety of mechanisms including (1) investigator initiated feasibility studies, (2) request for specific applications, (3) new technology development, (4) faculty recruitment, (5) state-of-the-art core development, (6) CFAR supplement applications, and (7) inter-center coordination. As a result of Developmental Core activities over a three year period, 12 new members have joined the CFAR, 5 manuscripts have been published, 5 national research grants totaling $2.9 million in direct costs, (including 1 minority supplement grant) have been funded, two new faculty members with a focus on AIDS-related research have been recruited to Case Western Reserve University, an ELIspot technology has been patented by Case Western Reserve University and provided as a service by a new CFAR Cytokine Core, thre other CFAR Cores have been enhanced, and several inter-center program initiatives have been developed. Developmental Core funds of $150,000/year are requested for years 06-10 to be used to support the Developmental Core programs as outlined above. In year 06, $75,000 will be used for faculty recruitment and the remained used to support investigator initiated feasibility studies and core development. In year 06 and in subsequent years, developmental Core funds will be distributed at the discretion of the CFAR leadership on a basis where the funds may have the greatest impact in stimulating AIDS-related research activities.