CORE--DEVELOPMENTAL

核心--发展

• 批准号: 6485952
• 负责人: JONATHAN P LEIS
• 金额: $ 19.62万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6485952
• 关键词: AIDS; biomedical facility; health science research support

The purpose of the CFAR Developmental Core is to stimulate the growth of AIDS-related research at Case Western Reserve University and its affiliates by fostering translational basic/clinical research developing experimental technologies whose application will advance AIDS-related research, promoting interactions with other Centers on the Case Western Reserve University campus. A Developmental Core administrative structure has been established to distribute and monitor the use of developmental funds through a variety of mechanisms including (1) investigator initiated feasibility studies, (2) request for specific applications, (3) new technology development, (4) faculty recruitment, (5) state-of-the-art core development, (6) CFAR supplement applications, and (7) inter-center coordination. As a result of Developmental Core activities over a three year period, 12 new members have joined the CFAR, 5 manuscripts have been published, 5 national research grants totaling $2.9 million in direct costs, (including 1 minority supplement grant) have been funded, two new faculty members with a focus on AIDS-related research have been recruited to Case Western Reserve University, an ELIspot technology has been patented by Case Western Reserve University and provided as a service by a new CFAR Cytokine Core, thre other CFAR Cores have been enhanced, and several inter-center program initiatives have been developed. Developmental Core funds of $150,000/year are requested for years 06-10 to be used to support the Developmental Core programs as outlined above. In year 06, $75,000 will be used for faculty recruitment and the remained used to support investigator initiated feasibility studies and core development. In year 06 and in subsequent years, developmental Core funds will be distributed at the discretion of the CFAR leadership on a basis where the funds may have the greatest impact in stimulating AIDS-related research activities.

CFAR 发展核心的目的是刺激增长 凯斯西储大学的艾滋病相关研究及其 通过促进转化基础/临床研究发展来建立附属机构 其应用将推进艾滋病相关的实验技术 研究，促进与 Case Western 其他中心的互动 保留大学校园。发展核心行政结构 已建立来分发和监测发展性资源的使用 通过多种机制提供资金，包括 (1) 研究者发起 可行性研究，(2) 具体申请请求，(3) 新 技术开发，(4) 教师招聘，(5) 最先进的核心 开发，(6) CFAR 补充应用，以及 (7) 中心间 协调。 由于三年期间发展核心活动的结果，12 CFAR新成员加入，已发表稿件5篇，5篇 国家研究补助金的直接费用总计 290 万美元，（包括 1 项少数族裔补充补助金）已获得资助，两名新教员 Case Western 招募了专注于艾滋病相关研究的研究人员 Reserve University 的 ELIspot 技术已获得 Case 的专利 西储大学并由新的 CFAR 作为服务提供 细胞因子核心、其他三个 CFAR 核心均已得到增强，还有几个 已经制定了中心间方案倡议。 06-10 年需要每年 150,000 美元的发展核心资金 用于支持上述发展核心计划。在 06年，$75,000将用于教师招聘，剩余的 用于支持研究者发起的可行性研究和核心 发展。在 06 年及随后几年，发展核心基金 将由 CFAR 领导层酌情分配 这些资金可能对刺激艾滋病相关工作产生最大影响 研究活动。