SKELETAL MUSCLE PERFUSION IN OXIDATIVE PHOSPHORYLATION IN OBESE INDIVIDUALS

肥胖个体氧化磷酸化中的骨骼肌灌注

• 批准号: 6123455
• 负责人: EDWARD G WALSH
• 金额: $ 0.42万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-05-01 至 2000-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6123455
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; biomedical resource; nuclear magnetic resonance spectroscopy; technology /technique

Generation of uniform radio frequency magnetic fields over a volume sufficient for whole body imaging at high field is not possible with conventional coil designs as seen in clinical scanners. This project will result in the development and implementation of an efficient, slotted cavity resonator design, which will provide for uniform imaging of the human thorax. Dr. Vaughan has successfully developed head coils of this design for use at field strengths as high as 9.4T. This experience, along with experience at UAB in successfully imaging most of the human heart using a surface coil for transmit and receive indicate high potential for successful implementation of a large volume coil for human imaging. This work is currently supported by two Small Business Technology Transfer grants with Enon Inc. (Dr. Vaughan as principal investigator).

均匀射频磁场的产生 不可能有足够的体积在高场进行全身成像 与临床扫描仪中所见的常规线圈设计一样。 这 该项目将导致制定和实施一项 有效的，开槽空腔谐振器设计，这将提供 人体胸部的均匀成像。 沃恩博士成功地 开发了这种设计的头部线圈，用于高场强 9.4T。 这种经验，沿着在UAB的经验， 使用表面线圈成功地对大部分人类心脏进行成像， 发送和接收表明成功的可能性很高 这是用于人体成像的大体积线圈的实现。 这项工作是 目前获得两项小企业技术转让赠款的支持 关于埃农公司(Dr. Vaughan作为首席研究员）。