IMAGING OF MYOCARDIAL INFARCTS IN SUDDEN DEATH

功能性MRI（fMRI）研究中的一个重要问题是 在以下范围内提供视觉刺激的满意手段： MRI系统，并立体地呈现这些刺激， 高空间分辨率。 第二个困难是需要 在眼部系统的fMRI研究中监视注视方向， 其中眼动响应的准确性对于 fMRI结果的解释。 视觉上的额外困难 呈现是监测对关于注视的指令的依从性， 方向，这可能是至关重要的功能磁共振成像结果的解释， 视觉系统的研究。 在这个项目中，这些问题是 回答了一个独特的光学系统兼容的建设 UAB 4.1T MRI系统的硬件。 正在建设中的系统包括一对高分辨率 LCD屏幕（800x600）可通过集成双目光学系统观看 系统，其中将包括对现有 计算机控制的基于ISCAN视频摄像机的眼睛监测系统 移动和注视方向。 安装定于1998年5月进行。 初步眼部功能磁共振成像结果获得之前， 在Kidambi S et. 例如，扫视过程中额叶眼区激活的fMRI检测 眼球运动，Proc Intl Soc Magn Reson Med 1844，1996。  光学 该系统在眼科和视觉相关功能磁共振成像中将是无价的 在许多fMRI研究中，非语言反应是 必需的. 它还将允许立体视觉和深度的视觉研究 perception. 因此，具有这种能力的系统将发现广泛的 在许多机构的功能磁共振成像研究中应用。 发展这一 该系统不仅将显著增强功能磁共振成像研究， 亚拉巴马大学伯明翰分校，但也将允许调查人员 在其他机构提供的技术， 显著增强了他们的功能磁共振成像研究。

A significant problem in functional MRI (fMRI) studies is a satisfactory means of presenting visual stimuli within the confines of the MRI system, and presenting these stimuli stereoscopically and at high spatial resolution. A second difficulty is the need for monitoring of gaze direction in fMRI studies of the oculomotor system, in which accuracy of oculomotor responses is of great importance in interpretation of fMRI results. An additional difficulty in visual presentation is monitoring compliance with instructions as to gaze direction, which can be crucial to interpretation of fMRI results in studies of the visual system. In this project these problems are answered with the construction of a unique optical system compatible with the hardware of the UAB 4.1T MRI system. The system under construction includes a pair of high-resolution LCD screens (800x600) to be viewed by an integrated binocular optical system, which will include an adaptation of an existing computer-controlled ISCAN video-camera-based system for monitoring eye movements and gaze direction. Installation is scheduled for May 1998. Preliminary oculomotor fMRI results obtained prior to the installation of the optical system have been reported in Kidambi S et al., fMRI Detection of Frontal Eye Field Activation during Saccadic Eye Movements, Proc Intl Soc Magn Reson Med 1844, 1996.  The optical system will be invaluable in oculomotor and vision-related fMRI studies and in many fMRI studies where non-verbal responses are required. It will also allow visual studies of stereopsis and depth perception. A system with this capability will thus find broad application in fMRI studies at many institutions. Development of this system will not only significantly enhance fMRI studies at the University of Alabama at Birmingham, but will also allow investigators at other institutions to be provided with the technology to significantly enhance their fMRI studies.