课题基金 / 基金详情

SAFETY, PHARMACOKINETIC/PHARMACODYNAMIC EFFECT OF PEG HIRUDIN ON ANTICOAGULATION

SAFETY, PHARMACOKINETIC/PHARMACODYNAMIC EFFECT OF PEG HIRUDIN ON ANTICOAGULATION
聚乙二醇水蛭素抗凝的安全性、药代动力学/药效学作用
批准号：
6115137
负责人：
JAMES H CHESEBRO
金额：
$6.88万
依托单位：
MOUNT SINAI SCHOOL OF MEDICINE OF CUNY
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/6115137
关键词：
angina pectoris cardiovascular disorder chemotherapy clinical research dosage drug screening /evaluation heparin hirudins human subject human therapy evaluation myocardial infarction pharmacokinetics

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中文摘要
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英文摘要
The objective of this study is to determine the optimal dosage of PEG- Hirudin in patients with unstable angina or non Q-wave myocardial infarction and also to compare its efficacy to that of standard drug therapy with heparin. The decision to give heparin, or to give PEG- Hirudin, will be made randomly by a computer after patient has given consent to participate.
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CLOPIDOGREL DOSING IN HUMAN ARTERIAL THROMBUS FORMATION
CLOPIDOGREL DOSING IN HUMAN ARTERIAL THROMBUS FORMATION
ANTITHROMBOTIC EFFECT OF ESCALATING DOSES OF PEG HIRUDIN IN HUMANS
LIPID LOWERING WITH SIMVASTATINE AFTER ACURE CORONARY SYNDROMES